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3/2006
vol. 108 abstract:
Original paper
Estimation of immunological markers in children with intermediate uveitis symptoms
Anna Turno-Kręcicka
1
,
Bożena Polańska
2
,
Maria Turska
1
,
Anna Barć
1
Online publish date: 2006/09/15
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Purpose
The purpose of this study was to estimate markers of immunological response in the blood of children with intermediate uveitis Material and methods : The records of 13 children (26 eyes), aged 10-17 years, with idiopathic intermediate uveitis were reviewed. In all cases indicators of inflammation and immunological response parameters were analyzed during the active stage of the disease. Results : In almost all patients ((90%) with intermediate uveitis disturbances in the level and activity of lymphocyte system, were detected. There were also nonspecific changes in immunoglobulins level in all patients, in 31% in more then one class of immunoglobulins. Chemiluminescence of phagocytic cells were reduced in more than 50% of children, and increase in their phagocytic activity was observed in 62% of patients. Circulating immune complexes were present in 50% of cases. Conclusions The study presents data supporting the theory of autoimmunological background of the intermediate uveitis. keywords:
intermediate uveitis, cystoid macular oedema, retinal vasculitis, immune system, lymphocytes, pathogenesis |
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POLSKI
