Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma

Krzysztof Cieślik; Anna Rogowska; Małgorzata Danowska; Karolina Trocka; Olga Rutynowska; Bożenna Dembowska-Bagińska; Wojciech Hautz

doi:10.5114/ko.2021.111472

POLSKI

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

Current issue Archive Videos Articles in press About the journal Supplements Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2022
vol. 124

Send email

Copy url:

abstract:

Original paper

Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma

Krzysztof Cieślik

¹

,

Anna Rogowska

¹

,

Małgorzata Danowska

¹

,

Karolina Trocka

¹

,

Olga Rutynowska

²

,

Bożenna Dembowska-Bagińska

²

,

Wojciech Hautz

¹

Department of Ophthalmology, Children’s Memorial Health Institute in Warsaw, Poland
Department of Oncology of the Children’s Memorial Health Institute in Warsaw, Poland

KLINIKA OCZNA 2022, 124, 1: 31–35

DOI: https://doi.org/10.5114/ko.2021.111472

Online publish date: 2022/01/05

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Cieślik K, Rogowska A, Danowska M, et al. Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma. Klinika Oczna / Acta Ophthalmologica Polonica. 2022;124(1):31-35. doi:10.5114/ko.2021.111472.

APA

Cieślik, K., Rogowska, A., Danowska, M., Trocka, K., Rutynowska, O.,  & Dembowska-Bagińska, B. et al. (2022). Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma. Klinika Oczna / Acta Ophthalmologica Polonica, 124(1), 31-35. https://doi.org/10.5114/ko.2021.111472

Chicago

Cieślik, Krzysztof, Anna Rogowska, Małgorzata Danowska, Karolina Trocka, Olga Rutynowska, Bożenna Dembowska-Bagińska,  and Wojciech Hautz. 2022. "Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma". Klinika Oczna / Acta Ophthalmologica Polonica 124 (1): 31-35. doi:10.5114/ko.2021.111472.

Harvard

Cieślik, K., Rogowska, A., Danowska, M., Trocka, K., Rutynowska, O., Dembowska-Bagińska, B.,  and Hautz, W. (2022). Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma. Klinika Oczna / Acta Ophthalmologica Polonica, 124(1), pp.31-35. https://doi.org/10.5114/ko.2021.111472

MLA

Cieślik, Krzysztof et al. "Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma." Klinika Oczna / Acta Ophthalmologica Polonica, vol. 124, no. 1, 2022, pp. 31-35. doi:10.5114/ko.2021.111472.

Vancouver

Cieślik K, Rogowska A, Danowska M, Trocka K, Rutynowska O, Dembowska-Bagińska B et al. Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma. Klinika Oczna / Acta Ophthalmologica Polonica. 2022;124(1):31-35. doi:10.5114/ko.2021.111472.

PlumX metrics:

Aim of the study
Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy (ICG-TTT) as a single treatment for recurrence of retinoblastoma.

Material and methods
Single-center, retrospective study of 18 procedures in 11 eyes of 11 retinoblastoma patients (12 tumors), with a mean follow-up of 31.94 months (range 1-44 months). Nine tumors had one procedure of ICG-TTT and 3 tumors had more than one procedure due to relapses. The technique involved applying thermotherapy (TTT) via an indirect ophthalmoscope 30 seconds after intravenous indocyanine administration at a dose of 0.6 mg/kg.

Results
During follow-up, tumor recurrence after ICG-TTT developed after 11 procedures. Taking into account cases where ICG-TTT was the only treatment for retinoblastoma relapse, the success rate was 26.7% (4 effective procedures out of 15). Overall, tumor control and globe salvage was achieved in all eyes with ICG-TTT alone or with other forms of therapy, e.g. systemic chemotherapy, ophthalmic artery chemosurgery, brachytherapy.

Conclusions
ICG-TTT as the only procedure for relapses of retinoblastoma has a moderate success rate. No ocular or systemic complications were noted.

keywords:

Evaluation of efficacy of indocyanine green enhanced transpupillary thermotherapy as a single treatment for recurrence of intraocular retinoblastoma

Krzysztof Cieślik 1 , Anna Rogowska 1 , Małgorzata Danowska 1 , Karolina Trocka 1 , Olga Rutynowska 2 , Bożenna Dembowska-Bagińska 2 , Wojciech Hautz 1

retinoblastoma, indocyanine, treatment, thermotherapy, laser

Krzysztof Cieślik

¹

,

Anna Rogowska

¹

,

Małgorzata Danowska

¹

,

Karolina Trocka

¹

,

Olga Rutynowska

²

,

Bożenna Dembowska-Bagińska

²

,

Wojciech Hautz

¹