Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography

Mustafa Ataş; Gökhan Açmaz; Hüseyin Aksoy; Süleyman Demircan; Altan Göktaş; Hasan Basri Arifoğlu; Gökmen Zararsız

doi:10.5114/pm.2014.41088

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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1/2014
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abstract:

Original paper

Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography

Mustafa Ataş

,

Gökhan Açmaz

,

Hüseyin Aksoy

,

Süleyman Demircan

,

Altan Göktaş

,

Hasan Basri Arifoğlu

,

Gökmen Zararsız

Prz Menopauzalny 2014; 13(1): 36-41

DOI: https://doi.org/10.5114/pm.2014.41088

Online publish date: 2014/03/10

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AMA

Ataş M, Açmaz G, Aksoy H, et al. Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography. Menopause Review/Przegląd Menopauzalny. 2014;13(1):36-41. doi:10.5114/pm.2014.41088.

APA

Ataş, M., Açmaz, G., Aksoy, H., Demircan, S., Göktaş, A.,  & Arifoğlu, H. et al. (2014). Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography. Menopause Review/Przegląd Menopauzalny, 13(1), 36-41. https://doi.org/10.5114/pm.2014.41088

Chicago

Ataş, Mustafa, Gökhan Açmaz, Hüseyin Aksoy, Süleyman Demircan, Altan Göktaş, Hasan Basri Arifoğlu,  and Gökmen Zararsız. 2014. "Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography". Menopause Review/Przegląd Menopauzalny 13 (1): 36-41. doi:10.5114/pm.2014.41088.

Harvard

Ataş, M., Açmaz, G., Aksoy, H., Demircan, S., Göktaş, A., Arifoğlu, H.,  and Zararsız, G. (2014). Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography. Menopause Review/Przegląd Menopauzalny, 13(1), pp.36-41. https://doi.org/10.5114/pm.2014.41088

MLA

Ataş, Mustafa et al. "Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography." Menopause Review/Przegląd Menopauzalny, vol. 13, no. 1, 2014, pp. 36-41. doi:10.5114/pm.2014.41088.

Vancouver

Ataş M, Açmaz G, Aksoy H, Demircan S, Göktaş A, Arifoğlu H et al. Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography. Menopause Review/Przegląd Menopauzalny. 2014;13(1):36-41. doi:10.5114/pm.2014.41088.

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Objective: Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period.

Aim of the study: To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in postmenopausal women and compare with healthy reproductive-age women controls.

Material and methods: The study population included a healthy reproductive-age control group (n = 72) and postmenopausal study group (n = 72). Retinal thickness parameters were measured by SD-OCT. Peripapillary RNFL thickness parameters, macular thickness and choroidal thickness were evaluated.

Results: Superior inner macula, temporal inner macula, inferior inner macula, nasal inner macula, inferior outer macula and choroid thickness were significantly thinner in the postmenopausal study group than the healthy reproductive-age control group (p = 0.007, p = 0.037, p = 0.027, p = 0.006, p = 0.016, p < 0.001, respectively). After adjusting for age, only choroid thickness was significantly thinner in the postmenopausal study group than controls (p† = 0.005).

Conclusions: This study revealed that choroidal thickness measured by SD-OCT was significantly thinner in postmenopausal women than healthy reproductive-age women. We can speculate that the decrease in choroidal thickness in postmenopausal women may indicate a reduced estrogen-dependent vasodilatory effect in ophthalmic artery secondary to menopausal estrogen deficiency.

keywords:

Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography

Mustafa Ataş , Gökhan Açmaz , Hüseyin Aksoy , Süleyman Demircan , Altan Göktaş , Hasan Basri Arifoğlu , Gökmen Zararsız

macula, retinal nerve fiber layer, choroid, menopause, optical coherence tomography

Mustafa Ataş

,

Gökhan Açmaz

,

Hüseyin Aksoy

,

Süleyman Demircan

,

Altan Göktaş

,

Hasan Basri Arifoğlu

,

Gökmen Zararsız