eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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4/2020
vol. 15
 
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abstract:
Review paper

Exocrine pancreatic insufficiency and causes of abdominal symptoms in diabetes patients

Roland Kadaj-Lipka
1
,
Grażyna Rydzewska
1, 2

  1. Clinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, Central Clinical Hospital of the MSWiA, Warsaw, Poland
  2. Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland
Gastroenterology Rev 2020; 15 (4): 289–293
Online publish date: 2020/12/10
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The pancreas has dual functions, endocrine and exocrine, that complement each other and work closely together, contributing to the digestion, absorption, and metabolism of foods. More than a decade ago, it was demonstrated that pancreatic exocrine insufficiency occurs in a significant number of patients with diabetes mellitus. Diabetes mellitus affects virtually every organ system in the body, and the degree of organ involvement depends on the duration and severity of the disease, as well as other co-morbidities. Gastrointestinal side effects include pancreatopathy, small intestinal bacterial overgrowth, oesophageal dysmotility, gastroesophageal reflux disease, gastroparesis, neuropathy, and nonalcoholic fatty liver disease.
keywords:

diabetes mellitus, pancreatic exocrine insufficiency, small intestinal bacterial overgrowth, gastroparesis, neuropathy

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