eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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4/2010
vol. 35
 
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abstract:

Experimental immunology
The influence of herbal remedies on cutaneous angiogenesis induced in mice after grafting of human kidney cancer tissue

Ewa Skopińska-Różewska
,
Krzysztof Pastewka
,
Aleksander Wasiutyński
,
Piotr Skopiński
,
Ewa Sommer
,
Dorota Siwicka

(Centr Eur J Immunol 2010; 35 (4): 199-203)
Online publish date: 2011/01/13
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The aim of the work was to study the effect of 5 herbal remedies with known immunostimulatory activity (Padma 28, Immunal forte, Reumaherb, Argoeleuter, Bioaron C) on neovascular reaction induced in the skin of Balb/c mice after grafting of human kidney cancer tissue homogenate or isolated tumor cells. Mice were fed remedies for 3 days following tumor grafting. Then, mice were sacrificed and newly formed blood vessels were counted in dissection microscope on the inner skin surface. Results: All tested remedies decreased cutaneous angiogenesis induced by human kidney cancer homogenate. In the case of cells isolated from tumor tissue, only Immunal forte diminished neovascular reaction.
keywords:

angiogenesis, mice, human kidney cancer, herbal remedies
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