Fetal microchimerism in a pregnant woman and risk of autoimmune disease

Karolina Hadasik; Beata Bergler-Czop; Ligia Brzezińska-Wcisło

doi:10.5114/dr.2018.75586

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

2/2018
vol. 105

Send email

Copy url:

abstract:

Case report

Fetal microchimerism in a pregnant woman and risk of autoimmune disease

Karolina Hadasik

,

Beata Bergler-Czop

,

Ligia Brzezińska-Wcisło

Dermatol Rev/Przegl Dermatol 2018, 105, 307-313

DOI: https://doi.org/10.5114/dr.2018.75586

Online publish date: 2018/05/14

View full text Get citation

PlumX metrics:

Autoimmune diseases most commonly affect women in their reproductive age. Many studies have attempted to link microchimeric fetal cells with the onset of autoimmune diseases after pregnancy. One of these diseases is localized scleroderma (morphea), which is a rare fibrosing disorder of the skin and underlying tissues. The etiology of morphea is unknown, but there are some predisposing factors that may induce morphea-like lesions. We present a rare case of a patient whose first cutaneous sclerotic lesions appeared in her 35th week of pregnancy. To our knowledge, to date pregnancy has not been treated as a predisposing factor for that disease, although it may be a risk factor, considering the phenomenon of fetal-maternal microchimerism.

keywords:

Fetal microchimerism in a pregnant woman and risk of autoimmune disease

Karolina Hadasik , Beata Bergler-Czop , Ligia Brzezińska-Wcisło

microchimerism, pregnancy, autoimmune disease, localized scleroderma

Karolina Hadasik

,

Beata Bergler-Czop

,

Ligia Brzezińska-Wcisło