Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis

Andrzej Kuźmiński; Justyna Przybyszewska; Zbigniew Bartuzi

doi:10.5114/pg.2024.139534

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

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abstract:

Review paper

Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis

Andrzej Kuźmiński

¹

,

Justyna Przybyszewska

²

,

Zbigniew Bartuzi

¹

Department of Allergology, Clinical Immunology, and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Jan Biziel University Hospital No. 2 in Bydgoszcz, Poland
Department of Nutrition and Dietetics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland

Gastroenterology Review

DOI: https://doi.org/10.5114/pg.2024.139534

Online publish date: 2024/05/13

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Eosinophilic esophagitis (EoE) is a chronic immune-mediated esophageal disease, clinically characterised by symptoms of esophageal dysfunction and histologically by eosinophilic infiltration of its wall. The last 3 decades have seen a sharp increase in its incidence to the point that it is called the second most common esophageal disease after reflux disease in some recent studies. The main indicators of EoE are food allergens and in recent years the extremely important role of oral immunotherapy (OIT) in the development of this disease has also been increasingly raised. To date, the appearance of EoE in the course of OIT is an absolute indication for discontinuation of this procedure; however, other therapeutic options that do not require termination of this procedure are increasingly being advocated. Unfortunately, our knowledge of EoE is full of gaps and requires numerous studies to fill in the missing elements of the pathogenesis and clinic of the described disease.

keywords:

Food allergens and oral immunotherapy as indicators of eosinophilic oesophagitis

Andrzej Kuźmiński 1 , Justyna Przybyszewska 2 , Zbigniew Bartuzi 1

eosinophilic oesophagitis, allergy, gastrointestinal tract

Andrzej Kuźmiński

¹

,

Justyna Przybyszewska

²

,

Zbigniew Bartuzi

¹