TP53 gene and p53 protein vs. endometrial carcinoma

Agnieszka Zając; Grzegorz Stachowiak; Tomasz Stetkiewicz; Jacek R. Wilczyński

doi:10.5114/pm.2013.36588

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

3/2013
vol. 12

Send email

Copy url:

abstract:

Review paper

TP53 gene and p53 protein vs. endometrial carcinoma

Agnieszka Zając

,

Grzegorz Stachowiak

,

Tomasz Stetkiewicz

,

Jacek R. Wilczyński

Przegląd Menopauzalny 2013; 17 (3): 228–230

DOI: https://doi.org/10.5114/pm.2013.36588

Online publish date: 2013/07/25

View full text Get citation

PlumX metrics:

The TP53 gene and its protein p53 play an important role in the cell cycle, DNA repair and apoptosis initiation. Genetic anomalies of TP53 are related to some neoplasms, including endometrial cancer. These alterations may initiate cancerogenesis within endometrium, being observed in type II and poorly-differentiated carcinomas. Immunoexpression of TP53/p53 may be helpful in the diagnostic and therapeutic process and be a prognostic factor for this carcinoma.

keywords:

TP53 gene and p53 protein vs. endometrial carcinoma

Agnieszka Zając , Grzegorz Stachowiak , Tomasz Stetkiewicz , Jacek R. Wilczyński

endometrial carcinoma, TP53, p53, menopause

Agnieszka Zając

,

Grzegorz Stachowiak

,

Tomasz Stetkiewicz

,

Jacek R. Wilczyński