Generalised pustular psoriasis – a case report and review of therapeutic approaches

Agnieszka Osmola-Mańkowska

doi:10.5114/dr.2014.46948

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

6/2014
vol. 101

Send email

Copy url:

abstract:

Original paper

Generalised pustular psoriasis – a case report and review of therapeutic approaches

Agnieszka Osmola-Mańkowska

Przegl Dermatol 2014, 101, 473-476

DOI: https://doi.org/10.5114/dr.2014.46948

Online publish date: 2014/11/25

View full text Get citation

PlumX metrics:

Introduction. Generalised pustular psoriasis (GPP) is regarded as a rare clinical subtype of psoriasis. The severity of GPP varies from a benign, chronic course to severe and widespread, life-threatening disease. Due to the uncommon nature of GPP, establishing treatment guidelines for this variant of psoriasis is challenging.

Objective. To present the case of a patient with GPP with a short review of therapeutic approaches.

Case report. Our patient was treated with standard methods such as acitretin, then cyclosporine and methotrexate as well as with biologic drug – infliximab. During the last and the most severe flare, combination therapy with systemic retinoid and PUVA (Re-PUVA) was used.

Conclusions. The treatment in GPP should be determined individually according to the severity of the disease, age, gender and comorbidities, as well as according to the physician’s experience with particular methods and their side effects. In addition, the availability of therapeutic options should be taken into consideration.

keywords:

Generalised pustular psoriasis – a case report and review of therapeutic approaches

Agnieszka Osmola-Mańkowska

psoriasis, pustular psoriasis, biologic therapy, TNF inhibitors, ustekinumab