HLA class I-matching in limbal stem cell
transplantation from living related donors

Edward Wylegala; Urszula Siekiera; Dorota Tarnowska; Bogusława Orzechowska-Wylęgała

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica Supplement

Current supplement Archive Acta Ophthalmologica Polonica

3/2004
vol. 106

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abstract:

Original paper

HLA class I-matching in limbal stem cell transplantation from living related donors

Edward Wylegala

¹

,

Urszula Siekiera

²

,

Dorota Tarnowska

¹

,

Bogusława Orzechowska-Wylęgała

¹

Z Oddziału Okulistyki Okręgowego Szpitala Kolejowego w Katowicach
Z Regionalnego Centrum Krwiodawstwa i Krwiolecznictwa w Katowicach Pracownia Immunogenetyki Układu HLA

KLINIKA OCZNA 2004, Supl. 3: S475–S477

Online publish date: 2022/12/29

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The cornea is an immune privileged site, but failure of corneal limbal stem cells is the cause of vascularisation, increasing the risk of immune response activity. The outcome after conjuctival limbal stem cells transplantation depends mainly on HLA system compatibility. HLA class I typing is one of the important factors considered in donor /recipient par matching. The aim of our study was the analysis of post transplant period in 16 related donor / recipient pars after limbal stem cells transplantation. We conclude that HLA class I and other immunogenetic factors compatibility (inside and out of the HLA region), may play the role in effective treatment.

keywords:

HLA class I-matching in limbal stem cell transplantation from living related donors

Edward Wylegala 1 , Urszula Siekiera 2 , Dorota Tarnowska 1 , Bogusława Orzechowska-Wylęgała 1

Limbal stem cells transplantation, HLA typing

Edward Wylegala

¹

,

Urszula Siekiera

²

,

Dorota Tarnowska

¹

,

Bogusława Orzechowska-Wylęgała

¹