Histopathological analysis of chronic gastritis and correlation of pathological features with each other and with endoscopic findings

Bhavna Garg; Vineet Sandhu; Neena Sood; Ajit Sood; Vineeta Malhotra

doi:10.5114/pjp.2012.31501

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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3/2012
vol. 63

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abstract:

Histopathological analysis of chronic gastritis and correlation of pathological features with each other and with endoscopic findings

Bhavna Garg

,

Vineet Sandhu

,

Neena Sood

,

Ajit Sood

,

Vineeta Malhotra

Pol J Pathol 2012; 3: 172-178

DOI: https://doi.org/10.5114/pjp.2012.31501

Online publish date: 2012/11/09

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Chronic gastritis is a very common disorder which is commonly caused by Helicobacter pylori. Histopathological examination is the mainstay of the diagnosis. We evaluated 300 gastric antral biopsies using revised Sydney system and concluded that it helps to analyse gastric biopsies in a very comprehensive manner. It was seen that H. pylori, chronic inflammatory infiltrate, neutrophilic infiltration, presence of lymphoid follicles and aggregates and surface epithelial damage are strongly associated with each other. The presence of one of these histological feature is a strong indicator for presence of other features. On the other hand intestinal metaplasia and atrophy of gastric glands was not associated with the above mentioned histological features. In the presence of dense chronic inflammation and infiltration by neutrophils one should carefully search for H. pylori organism. We also correlated histological features with endoscopy and found that cases of duodenal ulcer had more severe antral gastritis on histology as compared to those with hyperemia or antral erosions.

keywords:

Histopathological analysis of chronic gastritis and correlation of pathological features with each other and with endoscopic findings

Bhavna Garg , Vineet Sandhu , Neena Sood , Ajit Sood , Vineeta Malhotra

Helicobacter pylori, gastritis, inflammation

Bhavna Garg

,

Vineet Sandhu

,

Neena Sood

,

Ajit Sood

,

Vineeta Malhotra