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ISSN: 2392-1099
Clinical and Experimental Hepatology
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1/2020
vol. 6
 
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abstract:
Original paper

How close are we to hepatitis C virus elimination in Central Europe?

Robert Flisiak
1
,
Sona Frankova
2
,
Ivica Grgurevic
3
,
Bela Hunyady
4
,
Peter Jarcuska
5
,
Limas Kupčinskas
6
,
Michael Makara
7
,
Marieta Simonova
8
,
Jan Sperl
2
,
Ieva Tolmane
9
,
Adriana Vince
10
,
Dorota Zarębska-Michaluk
11

  1. Department of Infectious Diseases and Hepatology, Medical University of Białystok, Poland
  2. Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
  3. Department of Gastroenterology, Hepatology and Clinical Nutrition, University Hospital Dubrava, University of Zagreb School of Medicine, Croatia
  4. Department of Gastroenterology, Somogy County Kaposi Mór Teaching Hospital, Kaposvár and University of Pécs, Clinical Center, First Department of Medicine, Hungary
  5. 2nd Department of Internal Medicine, Louis Pasteur University Hospital and Pavol Jozej Šafárik University, Faculty of Medicine, Kosice, Slovakia
  6. Institute for Digestive Research and Department of Gastroenterology, Lithuanian University of Health Sciences, Kaunas, Lithuania
  7. Central Hospital of Southern Pest National Institute of Hematology and Infectious Diseases, Budapest, Hungary
  8. Department of Gastroenterology, HPB Surgery and Transplantology, Military Medical Academy, Sofia, Bulgaria
  9. Latvian Center of Infectious Diseases, Riga East University Hospital, Hepatology Department, University of Latvia, Faculty of Medicine, Latvia
  10. Department for Viral Hepatitis, University Hospital of Infectious Diseases, University of Zagreb School of Medicine, Zagreb, Croatia
  11. Department of Infectious Diseases, Jan Kochanowski University, Kielce, Poland
Clin Exp HEPATOL 2020; 6, 1: 1–8
DOI: https://doi.org/10.5114/ceh.2020.93049
Online publish date: 2020/02/17
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Aim of the study
To collect and analyse data obtained from HCV opinion leaders/experts from central European countries, on factors which can affect the WHO target of HCV elimination by 2030.

Material and methods
Data were collected from opinion leaders/experts involved in management of HCV infections in Central European countries which participated in 9th Conference of the Central European Hepatologic Collaboration (Warsaw, 10-11 October 2019). A dedicated questionnaire collected current information related to HCV elimination in Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia.

Results
The HCV prevalence rate in particular countries varied from 0.2% to 1.7%. In most central European countries all the HCV infected population is eligible for reimbursement of treatment. However, in some countries there are still some limitations related to the stage of the disease and people who inject drugs. All countries have access to at least one pangenotypic regimen. The most common barrier to HCV elimination in all countries is insufficient political will to establish priority for HCV. None of the reporting countries has established a national screening programme.

Conclusions
Access to therapy for HCV is similar and the majority of patients in Central Europe can be treated according to the current guidelines. Unfortunately there are still some limitations and a lack of political will to implement national screening programmes. According to collected data HCV elimination will not be possible in the region by 2030.

keywords:

therapy, liver, epidemiology, hepatitis C virus
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