Ta strona używa pliki cookies, w celu polepszenia użyteczności i funkcjonalności oraz w celach statystycznych. Dowiedz się więcej w Polityce prywatności.
Korzystając ze strony wyrażasz zgodę na używanie plików cookies, zgodnie z aktualnymi ustawieniami przeglądarki.
Akceptuję wykorzystanie plików cookies
Polish Journal of Thoracic and Cardiovascular Surgery
eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
1/2025
vol. 22
 
Share:
Send email
Share:
abstract:
Original paper

Immediate and long-term results of balloon aortic valvuloplasty for critical aortic valve stenosis in newborns. A single-center experience

Marek Rączka
1
,
Jacek Kuźma
2
,
Wanda Król
1
,
Piotr Weryński
1
,
Andrzej Rudziński
1
,
Janusz Hieronim Skalski
3
,
Sebastian Góreczny
1

  1. Department of Pediatric Cardiology, Jagiellonian University, Medical College, Krakow, Poland
  2. Cardiothoracic and Transplantology Department, Medical University of Warsaw, Warsaw, Poland
  3. Department of Pediatric Cardiac Surgery, Jagiellonian University, Medical College, Krakow, Poland
Kardiochirurgia i Torakochirurgia Polska 2025; 22 (1): 20-25
DOI: https://doi.org/10.5114/kitp.2025.148561
Online publish date: 2025/03/17
View full text Get citation
 
PlumX metrics:
Introduction:
Newborns with critical aortic valve stenosis (AVS) constitute a challenging group of patients, requiring urgent treatment, which in most centers is currently transcatheter balloon aortic valvuloplasty (BAV).

Aim:
Assessment the immediate and long-term outcome of BAV in newborns including preterm infants with critical AVS.

Material and methods:
We analyzed retrospectively 28 neonates (including 7 preterm infants) with critical AVS treated with the BAV procedure at mean age of 12.1 days. The mean follow-up period was 6.4 years. Patients were divided into 2 groups depending on the left ventricle ejection fraction (LVEF) ≤ 40% – group I (n = 12 patients, including 5 preterm infants) and > 40% – group II (n = 16 patients, including 2 prematures).

Results:
In both groups, the peak transvalvular pressure gradient across the aortic valve (TAPG) decreased significantly after BAV, whereas the mean LVEF increased significantly only in group I newborns. Various adverse events occurred in 6 (21.4%) newborns. A total of 12 (42.8%) children required re-intervention, including 1 child who underwent 3 procedures. They occurred slightly more often in children born prematurely (57.1%) compared to children born at term (38%). During follow-up, 6 patients died, 5 patients in group I and 1 in group II, including 3 of 7 preterm infants (all in group I). The Kaplan-Meier survival curve showed significantly higher mortality in group I patients (p = 0.03).

Conclusions:
BAV as the initial treatment for newborns with critical AVS gives satisfactory results, but further follow-up shows a frequent need for re-intervention. Significant LV systolic dysfunction and prematurity are risk factors for higher mortality in these patients.

keywords:

aortic valve stenosis, balloon aortic valvuloplasty, clinical outcomes, newborns, premature infants
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2025 Termedia Sp. z o.o.
Developed by Bentus.