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Family Medicine & Primary Care Review
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4/2021
vol. 23
 
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Original paper

Immediate fasting blood glucose response to electroacupuncture of ST36 versus CV 12 in patients with type 2 diabetes mellitus: randomized controlled trial

Ali Mohamed Ali Ismail
1
,
Alshaymaa Shaaban Abd El-Azeim
2

  1. Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt
  2. Basic Science Department, Faculty of Physical Therapy, Cairo University, Giza, Egypt
Family Medicine & Primary Care Review 2021; 23(4): 437–441
Online publish date: 2021/12/30
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1. Ismail AMA, Eld E, Abdel Aal MEM. Impact of transcutaneous electrical nerve stimulation (TENS) on hyposalivation in type 2 diabetics. Biosci Res 2019; 16(1): 690–694.
2. Ismail AMA, Abd El-Azeim AS. Short-term intraocular pressure response to the combined effect of transcutaneous electrical nerve stimulation over acupoint (Acu-TENS) and yoga ocular exercise in type 2 diabetic patients with primary open-angle glaucoma: a randomized controlled trial. J Acupunct Meridian Stud 2021; 14(5): 193–199.
3. Ismail AMA, Tolba AMN, Felaya EEE. Effect of aerobic exercise training on leptin and liver enzymes in non-diabetic overweight hepatitis C men. Advances in Rehabilitation 2021; 35(2): 17–23, doi: 10.5114/areh.2021.106027.
4. Lee YC, Li TM, Tzeng CY, et al. Electroacupuncture at the Zusanli (ST-36) acupoint induces a hypoglycemic effect by stimulating the cholinergic nerve in a rat model of streptozotocine-induced insulin-dependent diabetes mellitus. Evid Based Complementary Altern Med 2011; 2011: 650263, doi: 10.1093/ecam/neq068.
5. Zhou C. Nursing intervention on exercise therapy for patients with type 2 diabetes mellitus complicated with peripheral vascular disease. Acta Microsc 2020; 29(1); 439–446.
6. Ismail AMA, Abd Elfatah Abo Saif HF, El-Moatasem AMM. Effect of Jyoti-Trataka on intraocular pressure, autonomic control, and blood glucose in diabetic patients with high-tension primary open-angle glaucoma: a randomized-controlled trial. J Complement Integr Med 2021, doi: 10.1515/jcim-2021-0041.
7. Chang SL, Lin JG, Chi TC, et al. An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats. Diabetologia 1999; 42(2): 250–255, doi: 10.1007/s001250051146.
8. Chen C, Liu J, Sun M, et al. Acupuncture for type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract 2019; 36: 100–112, doi: 10.1016/j.ctcp.2019.04.004.
9. Ismail AMA, Abdelghany AI, Elfahl AMA. Immediate effect of interscapular cupping on blood pressure, oxygen saturation, pulse rate and chest expansion in sedentary smoker students. J Complement Integr Med 2021; 18(2): 391–396, doi: 10.1515/jcim-2020-0050.
10. Cheng H, Zhao L, Ju Z, et al. Effects of 10.6-μm laser moxibustion and electroacupuncture at ST36 in a 5-Fu-induced diarrhea rat model. Supportive Care Cancer 2020; 1–9, doi: 10.1007/s00520-020-05788-0.
11. Lin W, Jia D, Fu C, et al. Electro-acupuncture on ST36 and SP6 acupoints ameliorates lung injury via sciatic nerve in a rat model of limb ischemia-reperfusion. J Inflamm Res 2020; 13: 465, doi: 10.2147/JIR.S264093.
12. Lee CH, Kim DK, Yook TH, et al. Effectiveness of electroacupuncture at Zusanli (ST36) on the immunohistochemical density of enteroendocrine cells related to gastrointestinal function. J Acupunct Meridian Stud 2012; 5(2): 63–71, doi: 10.1016/j.jams.2012.01.002.
13. Lin RT, Tzeng CY, Lee YC, et al. Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats. BMC Complement Altern Med 2009; 9(1): 1–9, doi: 10.1186/1472-6882-9-26.
14. Wang LQ, Chen Z, Zhang K, et al. Zusanli (ST36) acupoint injection for diabetic peripheral neuropathy: a systematic review of randomized controlled trials. J Altern Complement Med 2018; 24(12): 1138–1149, doi: 10.1089/acm.2018.0053.
15. Lu Y, Ji B, Zhao G, et al. Comparison of protective effects of electroacupuncture at ST36 and LU5 on pulmonary and hypothalamic pituitary adrenal axis changes in perinatal nicotine-exposed rats. Biomed Res Int 2020, 2020: 3901528, doi: 10.1155/2020/3901528.
16. Rousdy A. Effectiveness of acupressure at the Zusanli (ST-36) acupoint as a comfortable treatment for diabetes mellitus: a pilot study in Indonesia. J Acupunct Meridian Stud 2017; 10(2): 96–103, doi: 10.1016/j.jams.2016.12.003.
17. Kim MS, Sung B, Ogay V, et al. Novel circulatory connection from the acupoint Zhong Wan (CV12) to pancreas. J Korean Pharmacopunct Inst 2008; 11(1): 13–19, doi: 10.3831/KPI.2008.11.1.013.
18. Kumar R, Mooventhan A, Manjunath NK. Immediate effect of needling at CV-12 (Zhongwan) acupuncture point on blood glucose level in patients with type 2 diabetes mellitus: a pilot randomized placebo-controlled trial. J Acupunct Meridian Stud 2017; 10(4): 240–244, doi: 10.1016/j.jams.2017.06.003.
19. Mooventhan A, Ningombam R, Nivethitha L. Effect of bilateral needling at an acupuncture point, ST-36 (Zusanli) on blood glucose levels in type 2 diabetes mellitus patients: a pilot randomized placebo controlled trial. J Complement Integr Med 2020; 7(3): 20190100, doi: 10.1515/jcim-2019-0100.
20. Cornejo-Garrido J, Becerril-Chavez F, Carlin-Vargas G, et al. Antihyperglycaemic effect of laseracupuncture treatment at BL20 in diabetic rats. Acupunct Med 2014; 32: 486–494, doi: 10.1136/acupmed-2014-010573.
21. Li YY, Hu H, Liang CM, et al. Effects of electroacupuncture stimulation of “Daimai” (GB 26) on body weight, blood glucose and blood lipid levels in rats with metabolism syndrome. Zhen Ci Yan Jiu 2014; 39: 202–206.
22. Gao L, Chen B, Zhang Q, et al. Acupuncture with different acupoint combinations for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial. BMC Complement Altern Med 2016; 16(1): 441, doi: 10.1186/s12906-016-1425-1.
23. Chen B, Hu SX, Liu BH, et al. Efficacy and safety of electroacupuncture with different acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial. Trials 2015; 16(1): 212, doi: 10.1186/s13063-015-0734-x.
24. Peplow PV, Baxter GD. Electroacupuncture for control of blood glucose in diabetes: literature review. J Acupunct Meridian Stud 2012; 5(1): 1–10, doi: 10.1016/j.jams.2011.11.018.
25. Gergess SH, Hesham AAR, Ghada S, et al. Effect of electroacupuncture on glucostasis in diabetic rats. Med J Cairo Univ 2018; 86: 3589–3596.
26. Chang SL, Tsai CC, Lin JG, et al. Involvement of serotonin in the hypoglycemic response to 2 Hz electroacupuncture of zusanli acupoint (ST36) in rats. Neurosci Lett 2005; 379(1): 69–73, doi: 10.1016/j.neulet.2004.12.057.
27. Chang CS, Ko CW, Wu CY, et al. Effect of electrical stimulation on acupuncture points in diabetic patients with gastric dysrhythmia: a pilot study. Digestion 2001; 64(3): 184–190, doi: 10.1159/000048860.
28. Mohanty S, Mooventhan A, Manjunath NK. Effect of Needling at CV-12 (Zhongwan) on blood glucose levels in healthy volunteers: a pilot randomized placebo controlled trial. J Acupunct Meridian Stud 2016; 9(6): 307–310, doi: /10.1016/j.jams.2016.08.002.
29. Chang SL, Lin JG, Hsieh CL, et al. Comparison of hypoglycemic effect in different acupoints response to 2Hz electroacupuncture. J Chin Med 2002; 13(2): 111–117.
Copyright: © 2021 Family Medicine & Primary Care Review. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
 
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