Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation

Piotr Chodór; Krzysztof Wilczek; Łukasz Włoch; Roman Przybylski; Jan Głowacki; Tomasz Kukulski; Tomasz Niklewski; Marian Zembala; Mariusz Gąsior; Zbigniew Kalarus

doi:10.5114/aic.2019.84394

eISSN: 1897-4295
ISSN: 1734-9338

Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej

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abstract:

Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation

Piotr Chodór

,

Krzysztof Wilczek

,

Łukasz Włoch

,

Roman Przybylski

,

Jan Głowacki

,

Tomasz Kukulski

,

Tomasz Niklewski

,

Marian Zembala

,

Mariusz Gąsior

,

Zbigniew Kalarus

Adv Interv Cardiol 2019; 15, 2 (56): 167–175

DOI: https://doi.org/10.5114/aic.2019.84394

Online publish date: 2019/04/09

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AMA

Chodór P, Wilczek K, Włoch Ł, et al. Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2019;15(2):167-175. doi:10.5114/aic.2019.84394.

APA

Chodór, P., Wilczek, K., Włoch, Ł., Przybylski, R., Głowacki, J.,  & Kukulski, T. et al. (2019). Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 15(2), 167-175. https://doi.org/10.5114/aic.2019.84394

Chicago

Chodór, Piotr, Krzysztof Wilczek, Łukasz Włoch, Roman Przybylski, Jan Głowacki, Tomasz Kukulski,  and Tomasz Niklewski et al. 2019. "Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 15 (2): 167-175. doi:10.5114/aic.2019.84394.

Harvard

Chodór, P., Wilczek, K., Włoch, Ł., Przybylski, R., Głowacki, J., Kukulski, T., Niklewski, T., Zembala, M., Gąsior, M.,  and Kalarus, Z. (2019). Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 15(2), pp.167-175. https://doi.org/10.5114/aic.2019.84394

MLA

Chodór, Piotr et al. "Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 15, no. 2, 2019, pp. 167-175. doi:10.5114/aic.2019.84394.

Vancouver

Chodór P, Wilczek K, Włoch Ł, Przybylski R, Głowacki J, Kukulski T et al. Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2019;15(2):167-175. doi:10.5114/aic.2019.84394.

Introduction
The presence of coronary artery disease (CAD) in patients who underwent transcatheter aortic valve implantation (TAVI) may increase in-hospital and long-term mortality.

Aim
To evaluate the impact of CAD in patients who underwent TAVI.

Material and methods
The study group consisted of the first 142 patients treated with TAVI between 26 November 2008 and 31 December 2015. The patients were divided into two groups: group I comprised 103 (72.5%) patients with CAD, and group II comprised 39 (27.5%) patients without CAD.

Results
Group I was characterized by a significantly higher risk according to EuroSCORE – 11.2 ±2.5 vs. 9 ±2.3 in group II (p < 0.001) and Logistic EuroSCORE – 25.4 ±13.4 vs. 16.3 ±8.7 (p < 0.001). 30-day mortality was 8 (7.8%) vs. 2 (5.1%) (p = NS) and 1-year mortality was 22 (21.4%) vs. 6 (15.4%) (p = NS) in group I and II respectively. The composite endpoint evaluating the efficacy of TAVI was achieved in 82 (79.6%) vs. 31 (79.5%) (p = NS) in group I and II respectively. The composite endpoint, which involved 30-day observation, occurred in 39 (37.86%) vs. 12 (30.77%) (p = NS) and the composite endpoint, which involved 1-year evaluation of the clinical efficacy of TAVI, occurred in 48 (57.8%) vs. 13 (48.1%) (p = NS) in patients with and without CAD respectively.

Conclusions
The short- and mid-term outcomes of TAVI patients with CAD, despite higher risk profile, did not differ from the outcomes of treatment in patients without CAD.

keywords:

Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation

Piotr Chodór , Krzysztof Wilczek , Łukasz Włoch , Roman Przybylski , Jan Głowacki , Tomasz Kukulski , Tomasz Niklewski , Marian Zembala , Mariusz Gąsior , Zbigniew Kalarus

percutaneous coronary intervention, coronary artery disease, coronary artery bypass graft, transcatheter aortic valve implantation

Piotr Chodór

,

Krzysztof Wilczek

,

Łukasz Włoch

,

Roman Przybylski

,

Jan Głowacki

,

Tomasz Kukulski

,

Tomasz Niklewski

,

Marian Zembala

,

Mariusz Gąsior

,

Zbigniew Kalarus