Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding

Angel Yordanov; Stoyan Kostov; Yavor Kornovski; Yonka Ivanova; Stanislav Slavchev; Gancho Kostov; Strahil Strashilov

doi:10.5114/pm.2022.124020

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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4/2022
vol. 21

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abstract:

Case report

Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding

Angel Yordanov

¹

,

Stoyan Kostov

²

,

Yavor Kornovski

³

,

Yonka Ivanova

³

,

Stanislav Slavchev

³

,

Gancho Kostov

⁴

,

Strahil Strashilov

⁵

Department of Gynaecological Oncology, Medical University Pleven, Pleven, Bulgaria
Department of Gynaecology, Medical University of Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
Department of Obstetrics and Gynaecology, Medical University of Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
Department of Special Surgery, University Hospital Kaspela, Plovdiv, Bulgaria
Department of Plastic Restorative, Reconstructive and Aesthetic Surgery, University Hospital “Dr. Georgi Stranski”, Medical University Pleven, Pleven, Bulgaria

Menopause Rev 2022; 21(4): 285-288

DOI: https://doi.org/10.5114/pm.2022.124020

Online publish date: 2022/12/30

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Introduction
Introduction: Renal cancer is the seventh most common cancer in men and the tenth most common cancer in women. Renal cell carcinoma accounts for 3% of all adult malignancies and 85% of all primary renal tumours. It metastasizes most often to the lungs, liver, bones, and brain and very rarely to the vagina.

Case Report
We present a case of a 60-year-old patient, in whom the renal cell carcinoma manifested for the first time as an intense bleeding, soft tumour formation with dimensions 4/6 cm originating in the vagina.

Discussion
Renal cell carcinoma metastasizes in about 30% of cases. Metastasizing can be lymphatic, hematogenous, transcoelomic, or by direct invasion. Most commonly it affects the lungs, bones, adrenal glands, liver, lymph nodes, and brain. Much less often, it metastasizes to the thyroid, orbit, nasal structures, vagina, gallbladder, pancreas, sublingual tissues, and soft tissues of distal extremities. Metastases can be synchronous and metachronous. The described cases in the literature of renal cell carcinoma manifested with vaginal metastases are isolated.

Conclusions
We present an extremely rare case of renal cell carcinoma manifested by profuse genital bleeding from a vaginal metastasis. In such cases, especially if the vaginal lesion does not appear as the primary vaginal carcinoma, we must consider the possibility of metastasis from renal carcinoma.

keywords:

Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding

Angel Yordanov 1 , Stoyan Kostov 2 , Yavor Kornovski 3 , Yonka Ivanova 3 , Stanislav Slavchev 3 , Gancho Kostov 4 , Strahil Strashilov 5

renal cell carcinoma; vaginal metastasis; diagnosis; treatment

Angel Yordanov

¹

,

Stoyan Kostov

²

,

Yavor Kornovski

³

,

Yonka Ivanova

³

,

Stanislav Slavchev

³

,

Gancho Kostov

⁴

,

Strahil Strashilov

⁵