Interdigitating dendritic cell sarcoma of lymph node mimicking granuloma: a case report and review  of the literature

Ziyin Ye; Fang Liu; Qinghua Cao; Hangliang Lin

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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4/2011
vol. 62

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abstract:

Interdigitating dendritic cell sarcoma of lymph node mimicking granuloma: a case report and review of the literature

Ziyin Ye

,

Fang Liu

,

Qinghua Cao

,

Hangliang Lin

POL J PATHOL 2011; 4: 274-277

Online publish date: 2012/01/10

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Interdigitating dendritic cell sarcoma (IDCS), is an extremely rare neoplasm. We report a case of a 77-year-old man presented with gradual lymph nodes enlargement in inguina, neck and axilla for 6 months. Biopsy revealed that part of the lymph node was replaced by several large granuloma-like nodules composed of mild atypical tumor cells, resembling epithelioid cells. Mitotic figures were hardly found. Immunohistochemistry showed that tumor cells were positive for S-100, CD68 and CD45. Ki-67 labeling index was 5%. To the best of our knowledge, this is the first case of IDCS showing granuloma-like growth pattern with mild atypical tumor cells.

keywords:

Interdigitating dendritic cell sarcoma of lymph node mimicking granuloma: a case report and review of the literature

Ziyin Ye , Fang Liu , Qinghua Cao , Hangliang Lin

hematology, interdigitating dendritic cell sarcoma, granuloma

Ziyin Ye

,

Fang Liu

,

Qinghua Cao

,

Hangliang Lin