Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients

Giovanni Cestaro; Michele De Rosa; Salvatore Massa; Bruno Amato; Maurizio Gentile

doi:10.5114/wiitm.2014.47435

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abstract:

Case report

Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients

Giovanni Cestaro

,

Michele De Rosa

,

Salvatore Massa

,

Bruno Amato

,

Maurizio Gentile

Videosurgery Miniinv 2015; 10 (2): 337–341

DOI: https://doi.org/10.5114/wiitm.2014.47435

Online publish date: 2014/12/04

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AMA

Cestaro G, Rosa M, Massa S, Amato B, Gentile M. Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients. Videosurgery and Other Miniinvasive Techniques. 2015:337-341. doi:10.5114/wiitm.2014.47435.

APA

Cestaro, G., Rosa, M., Massa, S., Amato, B.,  & Gentile, M. (2015). Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients. Videosurgery and Other Miniinvasive Techniques, 337-341. https://doi.org/10.5114/wiitm.2014.47435

Chicago

Cestaro, Giovanni, Michele De Rosa, Salvatore Massa, Bruno Amato,  and Maurizio Gentile. 2015. "Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients". Videosurgery and Other Miniinvasive Techniques: 337-341. doi:10.5114/wiitm.2014.47435.

Harvard

Cestaro, G., Rosa, M., Massa, S., Amato, B.,  and Gentile, M. (2015). Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients. Videosurgery and Other Miniinvasive Techniques, pp.337-341. https://doi.org/10.5114/wiitm.2014.47435

MLA

Cestaro, Giovanni et al. "Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients." Videosurgery and Other Miniinvasive Techniques, 2015, pp. 337-341. doi:10.5114/wiitm.2014.47435.

Vancouver

Cestaro G, Rosa M, Massa S, Amato B, Gentile M. Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients. Videosurgery and Other Miniinvasive Techniques. 2015:337-341. doi:10.5114/wiitm.2014.47435.

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Faecal incontinence is a very debilitating problem. Many techniques have been proposed to treat this condition, with controversial results. Autologous transplant of fat tissue is an established procedure used for the repair of tissue damage, and recent studies revealed the potentiality of tissue regeneration by human adipose-derived stem cells. We treated this condition with the injection, in the intersphincteric anal groove, of lipoaspirate processed by an innovative technology (Lipogems). The aim of the study was to evaluate the efficacy of Lipogems injection for the treatment of faecal incontinence. In February 2014 we treated 3 patients with faecal incontinence. The surgical procedure required three phases: lipoaspiration, processing of lipoaspirate with the Lipogems system, and injection of the obtained product in the intersphincteric anal groove. An accurate proctological examination followed at 1 week, 1 month and 6 months after treatment. Each patient reported an improved Wexner incontinence score at 1 month after the procedure. We observed an increase of resting pressure (by at least 10 mm Hg) and thickness of the internal anal sphincter respectively at ano-rectal manometry and by ultrasound (US) evaluation at the sixth month of follow-up. Our preliminary results are encouraging, but multicentric studies with longer follow-up are needed to validate this novel technique for treatment of faecal incontinence.

keywords:

Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients

Giovanni Cestaro , Michele De Rosa , Salvatore Massa , Bruno Amato , Maurizio Gentile

faecal incontinence, intersphincteric anal groove, lipofilling

Giovanni Cestaro

,

Michele De Rosa

,

Salvatore Massa

,

Bruno Amato

,

Maurizio Gentile