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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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3/2005
vol. 107
 
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abstract:
Review paper

Is it possible to diagnose lymphoproliferative lesions by fine needle aspiration biopsy?

Maria Chosia
1
,
Ewa Wolska-Szmidt
2

  1. Zakład Patomorfologii Pomorskiej Akademii Medycznej w Szczecinie
  2. Katedra i Klinika Okulistyki Pomorskiej Akademii Medycznej
Klinika Oczna 2005, 107(7-9): 555-559
Online publish date: 2005/09/22
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Despite the fact that fine needle aspiration biopsy (FNAB) is a commonly employed method in modern oncological diagnostic management, it has found no extensive use to diagnose lymphoproliferative lesions of the orbit and eye adnexa. Benign and malignant lymphoproliferative lesions and pseudotumor have a very similar clinical course. Microscopicaly, the lesions are also similar and hence even on histology it is difficult to differentiate between these conditions based on the morphology. We believed, that routine cytology and flow cytometry and/or PCR method in materials obtained in the course of FNAB are fast and sensitive methods and in many cases allow to avoid a surgical biopsy.
keywords:

orbit – eye adnexa – lymphoproliferative lesions – fine needle aspiration biopsy – flow cytometry – PCR

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