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ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
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1/2024
vol. 99
 
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abstract:
Review paper

Kawasaki disease – characteristics, diagnosis, and management

Yevheniia Popravko
1
,
Nikola Siekierko
1
,
Wiktoria Kotusiewicz
2
,
Mateusz Lewandowski
3
,
Maja Żołnierek
4
,
Zuzanna Lubczyńska
5
,
Jakub Świętochowski
6
,
Grzegorz Bienia
2

  1. Praski State Hospital, Warsaw, Poland
  2. Military Institute of Medicine-National Research Institute, Warsaw, Poland
  3. University Clinical Centre of the Medical University of Warsaw, Warsaw, Poland
  4. St. John Paul II’s Western Hospital of Grodzisk Mazowiecki, Poland
  5. The Rafal Mashtak Hospital of Grochów, Warsaw, Poland
  6. The University Clinical Centre in Gdańsk, Gdańsk, Poland
Pediatr Pol 2024; 99 (1): 46-52
DOI: https://doi.org/10.5114/polp.2024.135987
Online publish date: 2024/03/06
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Kawasaki disease (KD) is an acute systemic vasculitis of medium – sized vessels that affects infants and children. The etiology of KD is unclear. Typical KD requires the presence of fever of at least 5 days duration and coexisting ≥ 4/5 principal clinical features: bilateral bulbar conjunctival injection, erythema and cracking og lips, skin rash, erythema and edema of the palms and feet, unilateral cervical nonpurulent lymphadenopathy. If patient presents less than 4 of the principal clinical features, the diagnosis of incomplete KD should be considered. The basis of initiate treatment of KD is a single dose of intravenous immunoglobulin (IVIG) with acetylsalicylic acid. But about 10–20% of patients do not respond to IVIG-therapy. Timely and adequate treatment of KD by IVIG and aspirin could help to prevent the development of coronary artery lesions, thats why diagnosis of KD is very important.
keywords:

coronary artery aneurysm, Kawasaki disease, infliximab