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1/2024
vol. 99 abstract:
Review paper
Kawasaki disease – characteristics, diagnosis, and management
Yevheniia Popravko
1
,
Nikola Siekierko
1
,
Wiktoria Kotusiewicz
2
,
Mateusz Lewandowski
3
,
Maja Żołnierek
4
,
Zuzanna Lubczyńska
5
,
Jakub Świętochowski
6
,
Grzegorz Bienia
2
Pediatr Pol 2024; 99 (1): 46-52
Online publish date: 2024/03/06
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Kawasaki disease (KD) is an acute systemic vasculitis of medium – sized vessels that affects infants and children. The etiology of KD is unclear. Typical KD requires the presence of fever of at least 5 days duration and coexisting ≥ 4/5 principal clinical features: bilateral bulbar conjunctival injection, erythema and cracking og lips, skin rash, erythema and edema of the palms and feet, unilateral cervical nonpurulent lymphadenopathy. If patient presents less than 4 of the principal clinical features, the diagnosis of incomplete KD should be considered. The basis of initiate treatment of KD is a single dose of intravenous immunoglobulin (IVIG) with acetylsalicylic acid. But about 10–20% of patients do not respond to IVIG-therapy. Timely and adequate treatment of KD by IVIG and aspirin could help to prevent the development of coronary artery lesions, thats why diagnosis of KD is very important.
keywords:
coronary artery aneurysm, Kawasaki disease, infliximab |
POLSKI
