Mechanical thrombectomy for rescue treatment of severe thrombosis of the superior sagittal sinus with the use of Penumbra and AngioJet catheters

Thrombosis of the superior sagittal sinus (SSS) is a rare pathology, yet associated with high morbidity and mortality (5–20%). Routine management comprise anticoagulation with heparin and/or systemic fibrinolysis. Still, patients with life-threatening thrombosis of SSS, not improving after standard treatment or with contraindications for fibrinolysis, require endovascular management [1, 2].
Here we present a case of mechanical thrombectomy as rescue treatment for severe thrombosis of SSS in 21-year-old female patient. She developed acute neurologic symptoms 17 days after uncomplicated physiological labour. These comprised severe headache followed by left-sided hemiparesis and lethargy. Computed tomography (CT) angiography revealed thrombosis of SSS and infarction in the right hemisphere, with foci of haemorrhagic transformation and cerebral oedema. Considering contraindications for thrombolysis and expanding oedema, we decided to address thrombosis using mechanical thrombectomy. Catheter angiography revealed patent cerebral arteries and confirmed occlusion of the SSS (Figure 1 A). Using femoral vein access, we cannulated right internal jugular vein and over the 0.014” Traxcess® (Microvention, Aliso Viejo, CA, USA) guidewire, we introduced the Penumbra 5MAX™ ACE catheter (Penumbra Inc., Alameda, CA, USA) into the SSS. Several passages of this reperfusion catheter removed thrombi from the SSS (Figure 1 B). Then, through this catheter we introduced the 4 Fr AngioJetTM rheolytic catheter (Boston Scientific, Natick, MA, USA) and removed thrombi from proximal part of the SSS, confluence of sinuses and right transverse sinus, achieving good outflow (Figures 1 C, D).
After endovascular procedure patient was transmitted to the intensive care unit. She was anticoagulated with heparin. During her hospital stay there were several seizure episodes that required administration of antiepileptic agents. From the 8th postprocedural day she was conscious, free of seizures and without neurologic deficits. She was discharged with the recommendation of anticoagulation with warfarin and antiepileptic therapy with sodium valproate for 9 months. There were no new neurologic events revealed at follow-up 4 months after the procedure.
Patients with rapidly progressing thrombosis of SSS resulting in stroke or mass effect require an aggressive endovascular management. Mortality in patients with severe thrombosis of the SSS who are managed using mechanical...


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