eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
4/2024
vol. 19
 
Share:
Share:
Review paper

Microbiota modifications in prehabilitation – the next step towards comprehensive preparation for surgery. The scoping review

Igor Łoniewski
1
,
Tomasz Banasiewicz
2
,
Jerzy Sieńko
3
,
Karolina Skonieczna-Zydecka
1
,
Ewa Stachowska
4

  1. Department of Biochemical Science, Pomeranian Medical University, Szczecin, Poland
  2. Department of General Surgery, Endo- and Gastroenterological Oncology, Poznan University of Medical Sciences, Poznan, Poland
  3. Institute of Physical and Cultural Sciences, University of Szczecin, Szczecin, Poland
  4. Department of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland
Gastroenterology Rev 2024; 19 (4): 347–361
Online publish date: 2024/12/11
Article file
Get citation
 
PlumX metrics:
 
1. Jeske P, Wojtera B, Banasiewicz T, et al. Prehabilitacja – obecna rola w chirurgii. Pol J Surg 2022; 94: 64-72.
2. Banasiewicz T, Kobiela J, Cwaliński J, et al. Rekomendacje w zakresie stosowania prehabilitacji, czyli kompleksowego przygotowania pacjenta do zabiegu operacyjnego. Pol Przegl Chir 2023; 95: 61-91.
3. Ross FC, Patangia D, Grimaud G, et al. The interplay between diet and the gut microbiome: implications for health and disease. Nat Rev Microbiol 2024; 22: 671-86.
4. Patangia DV, Anthony Ryan C, Dempsey E, et al. Impact of antibiotics on the human microbiome and consequences for host health. Microbiol Open 2022; 11: e1260.
5. Maier L, Pruteanu M, Kuhn M, et al. Extensive impact of non-antibiotic drugs on human gut bacteria. Nature 2018; 555: 623-8.
6. Liu F, Duan M, Fu H, et al. Orthopedic surgery causes gut microbiome dysbiosis and intestinal barrier dysfunction in prodromal Alzheimer disease patients: a prospective observational cohort study. Ann Surg 2022; 276: 270-80.
7. Long DR, Bryson-Cahn C, Waalkes A, et al. Contribution of the patient microbiome to surgical site infection and antibiotic prophylaxis failure in spine surgery. Sci Transl Med 2024; 16: eadk8222.
8. Gilbert JA, Alverdy J. Where do the pathogens that cause surgical site infections come from? Sci Transl Med 2024; 16: eado1449.
9. Trone K, Rahman S, Green CH, et al. Synbiotics and surgery: can prebiotics and probiotics affect inflammatory surgical outcomes? Curr Nutr Rep 2023; 12: 238-46.
10. La Fata G, Weber P, Mohajeri MH, et al. Probiotics and the gut immune system: indirect regulation. Probiotics Antimicrob Proteins 2018; 10: 11-21.
11. Mazziotta C, Tognon M, Martini F, et al. Probiotics mechanism of action on immune cells and beneficial effects on human health. Cells 2023; 12: 184.
12. Hiippala K, Jouhten H, Ronkainen A, et al. The potential of gut commensals in reinforcing intestinal barrier function and alleviating inflammation. Nutrients 2018; 10: 988.
13. Wang X, Zhang P, Zhang X, et al. Probiotics regulate gut microbiota: an effective method to improve immunity. Molecules 2021; 26: 6076.
14. Salminen S, Collado MC, Endo A, et al. The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nat Rev Gastroenterol Hepatol 2021; 18: 649-67.
15. Skonieczna-Żydecka K, Kaczmarczyk M, Łoniewski I, et al. A systematic review, meta-analysis, and meta-regression evaluating the efficacy and mechanisms of action of probiotics and synbiotics in the prevention of surgical site infections and surgery-related complications. J Clin Med 2018; 7: 556.
16. Matzaras R, Nikopoulou A, Protonotariou E, et al. Gut microbiota modulation and prevention of dysbiosis as an alternative approach to antimicrobial resistance: a narrative review. Yale J Biol Med 2022; 95: 479-94.
17. Agnes A, Puccioni C, D’Ugo D, et al. The gut microbiota and colorectal surgery outcomes: facts or hype? A narrative review. BMC Surg 2021; 21: 83.
18. Ciobârcă D, Cătoi AF, Copăescu C, et al. Bariatric surgery in obesity: effects on gut microbiota and micronutrient status. Nutrients 2020; 12: 235.
19. Pohl JM, Gutweiler S, Thiebes S, et al. Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus. Gut 2017; 66: 2110-20.
20. Kotzampassi K. Why give my surgical patients probiotics. Nutrients 2022; 14: 4389.
21. Ye W, Dong B, Li G, et al. The effect of probiotics on surgical outcomes in patients with gastric cancer: a meta-analysis of randomized controlled trials. Front Surg 2023; 10: 1254597.
22. Fyntanidou B, Amaniti A, Soulioti E, et al. Probiotics in postoperative pain management. J Pers Med 2023; 13: 1645.
23. Ioannidis O, Chatzakis C, Tirta M, et al. The efficacy of probiotics, prebiotics, and synbiotics in patients who have undergone abdominal operation, in terms of bowel function post-operatively: a network meta-analysis. J Clin Med 2023; 12: 4150.
24. Matzaras R, Anagnostou N, Nikopoulou A, et al. The role of probiotics in inflammation associated with major surgery: a narrative review. Nutrients 2023; 15: 1331.
25. An S, Kim K, Kim MH, et al. Perioperative probiotics application for preventing postoperative complications in patients with colorectal cancer: a systematic review and meta-analysis. Medicina (Kaunas) 2022; 58: 1644.
26. Veziant J, Bonnet M, Occean BV, et al. Probiotics/synbiotics to reduce infectious complications after colorectal surgery: a systematic review and meta-analysis of randomised controlled trials. Nutrients 2022; 14: 3066.
27. Araújo MM, Montalvão-Sousa TM, Teixeira P da C, et al. The effect of probiotics on postsurgical complications in patients with colorectal cancer: a systematic review and meta-analysis. Nutr Rev 2023; 81: 493-510.
28. Ouyang X, Li Q, Shi M, et al. Probiotics for preventing postoperative infection in colorectal cancer patients: a systematic review and meta-analysis. Int J Colorectal Dis 2019; 34: 459-69.
29. Amitay EL, Carr PR, Gies A, et al. Probiotic/synbiotic treatment and postoperative complications in colorectal cancer patients: systematic review and meta-analysis of randomized controlled trials. Clin Transl Gastroenterol 2020; 11: e00268.
30. Kanazawa H, Nagino M, Kamiya S, et al. Synbiotics reduce postoperative infectious complications: a randomized controlled trial in biliary cancer patients undergoing hepatectomy. Langenbecks Arch Surg 2005; 390: 104-13.
31. Tang G, Zhang L, Tao J, et al. Effects of perioperative probiotics and synbiotics on pancreaticoduodenectomy patients: a meta-analysis of randomized controlled trials. Front Nutr 2021; 8: 715788.
32. Eguchi S, Takatsuki M, Hidaka M, et al. Perioperative synbiotic treatment to prevent infectious complications in patients after elective living donor liver transplantation: a prospective randomized study. Am J Surg 2011; 201: 498-502.
33. Sawas T, Al Halabi S, Hernaez R, et al. Patients receiving prebiotics and probiotics before liver transplantation develop fewer infections than controls: a systematic review and meta-analysis. Clin Gastroenterol Hepatol 2015; 13: 1567-74.e3.
34. Chowdhury AH, Adiamah A, Kushairi A, et al. Perioperative probiotics or synbiotics in adults undergoing elective abdominal surgery: a systematic review and meta-analysis of randomized controlled trials. Ann Surg 2020; 271: 1036-47.
35. Pitsouni E, Alexiou V, Saridakis V, et al. Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials. Eur J Clin Pharmacol 2009; 65: 561-70.
36. Kinross JM, Markar S, Karthikesalingam A, et al. A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? JPEN J Parenter Enteral Nutr 2013; 37: 243-53.
37. Kasatpibal N, Whitney JD, Saokaew S, et al. Effectiveness of probiotic, prebiotic, and synbiotic therapies in reducing postoperative complications: a systematic review and network meta-analysis. Clin Infect Dis 2017; 64: S153-60.
38. Cheema HA, Shahid A, Ayyan M, et al. Probiotics for the prevention of ventilator-associated pneumonia: an updated systematic review and meta-analysis of randomised controlled trials. Nutrients 2022; 14: 1600.
39. Watkinson PJ, Barber VS, Dark P, et al. The use of pre-, pro- and synbiotics in adult intensive care unit patients: systematic review. Clin Nutr 2007; 26: 182-92.
40. Sharif S, Greer A, Skorupski C, et al. Probiotics in critical illness: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med 2022; 50: 1175-86.
41. Shimizu K, Ogura H, Kabata D, et al. Association of prophylactic synbiotics with reduction in diarrhea and pneumonia in mechanically ventilated critically ill patients: a propensity score analysis. J Infect Chemother 2018; 24: 795-801.
42. Virk HS, Wiersinga WJ, et al. Current place of probiotics for VAP. Crit Care 2019; 23: 46.
43. Morrow LE, Gogineni V, Malesker MA, et al. Probiotic, prebiotic, and synbiotic use in critically ill patients. Curr Opin Crit Care 2012; 18: 186-91.
44. Fan QL, Yu XM, Liu QX, et al. Synbiotics for prevention of ventilator-associated pneumonia: a probiotics strain-specific network meta-analysis. J Int Med Res 2019; 47: 5349-74.
45. Chen J, Liang H, Lu J, et al. Probiotics improve postoperative adaptive immunity in colorectal cancer patients: a systematic review and meta-analysis. Nutr Cancer 2022; 74: 2975-82.
46. Chen Y, Qi A, Teng D, et al. Probiotics and synbiotics for preventing postoperative infectious complications in colorectal cancer patients: a systematic review and meta-analysis. Tech Coloproctol 2022; 26: 425-36.
47. Zeng J, Ji Y, Liang B, et al. The effect of pro/synbiotics on postoperative infections in colorectal cancer patients: a systematic review and meta-analysis. Complement Ther Clin Pract 2021; 43: 101370.
48. Xu J, Xu Y, Song Y, et al. Efficacy of probiotics supplementation on the prognosis of patients after liver transplantation: a systematic review and meta-analysis. Indian J Surg 2022; 84: 409-17.
49. Chen J, Zhao J, Wu H, et al. Efficacy and safety of oral probiotic supplementation in mitigating postoperative surgical site infections in patients undergoing colorectal cancer surgery: a systematic review and meta-analysis. Int Wound J 2024; 21: e14603.
50. Jiang J, Ren F, et al. Effect of probiotics and synbiotics on complications of wound infection after colorectal surgery: a meta-analysis. Int Wound J 2024; 21: e14838.
51. Lytvyn L, Quach K, Banfield L, et al. Probiotics and synbiotics for the prevention of postoperative infections following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials. J Hosp Infect 2016; 92: 130-9.
52. Liu PC, Yan YK, Ma YJ, et al. Probiotics reduce postoperative infections in patients undergoing colorectal surgery: a systematic review and meta-analysis. Gastroenterol Res Pract 2017; 2017: 6029075.
53. Tzikos G, Tsalkatidou D, Stavrou G, et al. A four-probiotic regime to reduce surgical site infections in multi-trauma patients. Nutrients 2022; 14: 2620.
54. Poutahidis T, Kearney SM, Levkovich T, et al. Microbial symbionts accelerate wound healing via the neuropeptide hormone oxytocin. PLoS One 2013; 8: e78898.
55. Bekiaridou A, Karlafti E, Oikonomou IM, et al. Probiotics and their effect on surgical wound healing: a systematic review and new insights into the role of nanotechnology. Nutrients 2021; 13: 4265.
56. Zeng J, Wang CT, Zhang FS, et al. Effect of probiotics on the incidence of ventilator-associated pneumonia in critically ill patients: a randomized controlled multicenter trial. Intensive Care Med 2016; 42: 1018-28.
57. Bo L, Li J, Tao T, et al. Probiotics for preventing ventilator-associated pneumonia. Cochrane Database Syst Rev 2014; 2014: CD009066.
58. Mahmoodpoor A, Hamishehkar H, Asghari R, et al. Effect of a probiotic preparation on ventilator-associated pneumonia in critically ill patients admitted to the intensive care unit: a prospective double-blind randomized controlled trial. Nutr Clin Pract 2019; 34: 156-62.
59. Dang AT, Marsland BJ, et al. Microbes, metabolites, and the gut–lung axis. Mucosal Immunol 2019; 12: 843-50.
60. Wu XD, Xu W, Liu MM, et al. Efficacy of prophylactic probiotics in combination with antibiotics versus antibiotics alone for colorectal surgery: a meta-analysis of randomized controlled trials. J Surg Oncol 2018; 117: 1394-404.
61. Dudzicz S, Kujawa-Szewieczek A, Kwiecień K, et al. Lactobacillus plantarum 299v reduces the incidence of Clostridium difficile infection in nephrology and transplantation ward-results of one year extended study. Nutrients 2018; 10: 1574.
62. Grąt M, Wronka KM, Lewandowski Z, et al. Effects of continuous use of probiotics before liver transplantation: a randomized, double-blind, placebo-controlled trial. Clin Nutr 2017; 36: 1530-9.
63. Rayes N, Hansen S, Seehofer D, et al. Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery. Nutrition 2002; 18: 609-15.
64. Wibawa IDN, Mariadi IK, Shalim CP, et al. Efficacy of probiotics in the treatment of minimal hepatic encephalopathy: a systematic review and meta-analysis. Clin Exp Hepatol 2023; 9: 146-53.
65. Kok DE, Arron MNN, Huibregtse T, et al. Association of habitual preoperative dietary fiber intake with complications after colorectal cancer surgery. JAMA Surg 2021; 156: 1-10.
66. Rousseaux C, Thuru X, Gelot A, et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 2007; 13: 35-7.
67. Chen C, Wen T, Zhao Q, et al. Probiotics used for postoperative infections in patients undergoing colorectal cancer surgery. Biomed Res Int 2020; 2020: 5734718.
68. Theodoropoulos GE, Memos NA, Peitsidou K, et al. Synbiotics and gastrointestinal function-related quality of life after elective colorectal cancer resection. Ann Gastroenterol 2016; 29: 56-62.
69. Głuszek S, Głuszek-Osuch M, Kozieł D, et al. Prehabilitation in preparing patients with inflammatory bowel diseases for surgery, including nutritional treatment and psychological support. Med Stud 2023; 39: 91-7.
70. Chen M, Feng Y, Liu W, et al. Efficacy and safety of probiotics in the induction and maintenance of inflammatory bowel disease remission: a systematic review and meta-analysis. Ann Palliat Med 2021; 10: 11821-9.
71. Dharmani P, De Simone C, Chadee K, et al. The probiotic mixture VSL#3 accelerates gastric ulcer healing by stimulating vascular endothelial growth factor. PLoS One 2013; 8: e58671.
72. Bischoff SC, Bager P, Escher J, et al. ESPEN guideline on clinical nutrition in inflammatory bowel disease. Clin Nutr 2023; 42: 352-79.
73. Quante AS, Ming C, Rottmann M, et al. Projections of cancer incidence and cancer-related deaths in Germany by 2020 and 2030. Cancer Med 2016; 5: 2649-56.
74. Strobel O, Neoptolemos J, Jäger D, et al. Optimizing the outcomes of pancreatic cancer surgery. Nat Rev Clin Oncol 2019; 16: 11-26.
75. Müssle B, Hempel S, Kahlert C, et al. Prognostic impact of bacterobilia on morbidity and postoperative management after pancreatoduodenectomy: a systematic review and meta-analysis. World J Surg 2018; 42: 2951-62.
76. Pretzsch E, Heim A, Heiliger C, et al. Specific intraoperative antibiotic therapy abrogates the negative effect of biliary contamination on the Comprehensive Complication Index after pancreatic head resection. Surgery 2022; 171: 1642-51.
77. Stein-Thoeringer CK, Renz BW, De Castilhos J, et al. Microbiome dysbiosis with enterococcus presence in the upper gastrointestinal tract is a risk factor for mortality in patients undergoing surgery for pancreatic cancer. Ann Surg 2024. doi: 10.1097/SLA.0000000000006210.
78. Correia MITD, Liboredo JC, Consoli MLD, et al. The role of probiotics in gastrointestinal surgery. Nutrition 2012; 28: 230-4.
79. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005; 115: 178-81.
80. Besselink MG, van Santvoort HC, Buskens E, et al. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet 2008; 371: 651-9.
81. Reid G, Gibson G, Sanders ME, et al. Probiotic prophylaxis in predicted severe acute pancreatitis. Lancet 2008; 372: 112-3.
82. Expression of concern -- Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet 2010; 375: 875-6.
83. Liu D, Jiang XY, Zhou LS, et al. Effects of probiotics on intestinal mucosa barrier in patients with colorectal cancer after operation: meta-analysis of randomized controlled trials. Medicine (Baltimore) 2016; 95: e3342.
84. Pitsillides L, Pellino G, Tekkis P, et al. The effect of perioperative administration of probiotics on colorectal cancer surgery outcomes. Nutrients 2021; 13: 1451.
85. Liu ZH, Huang MJ, Zhang XW, et al. The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial. Am J Clin Nutr 2013; 97: 117-26.
86. Liu Z, Qin H, Yang Z, et al. Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery – a double-blind study. Aliment Pharmacol Ther 2011; 33: 50-63.
87. Liu Z, Li C, Huang M, et al. Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical trial. BMC Gastroenterol 2015; 15: 34.
88. Komatsu S, Sakamoto E, Norimizu S, et al. Efficacy of perioperative synbiotics treatment for the prevention of surgical site infection after laparoscopic colorectal surgery: a randomized controlled trial. Surg Today 2016; 46: 479-90.
89. Sugawara G, Nagino M, Nishio H, et al. Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized controlled trial. Ann Surg 2006; 244: 706-14.
90. Okazaki M, Matsukuma S, Suto R, et al. Perioperative synbiotic therapy in elderly patients undergoing gastroenterological surgery: a prospective, randomized control trial. Nutrition 2013; 29: 1224-30.
91. Tanaka K, Yano M, Motoori M, et al. Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial. Surgery 2012; 152: 832-42.
92. Reddy BS, Macfie J, Gatt M, et al. Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy. Br J Surg 2007; 94: 546-54.
93. Zhang JW, Du P, Gao J, et al. Preoperative probiotics decrease postoperative infectious complications of colorectal cancer. Am J Med Sci 2012; 343: 199-205.
94. Tang G, Huang W, Tao J, et al. Prophylactic effects of probiotics or synbiotics on postoperative ileus after gastrointestinal cancer surgery: a meta-analysis of randomized controlled trials. PLoS One 2022; 17: e0264759.
95. Goodman C, Keating G, Georgousopoulou E, et al. Probiotics for the prevention of antibiotic-associated diarrhoea: a systematic review and meta-analysis. BMJ Open 2021; 11: e043054.
96. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA 2012; 307: 1959-69.
97. Mizuta M, Endo I, Yamamoto S, et al. Perioperative supplementation with bifidobacteria improves postoperative nutritional recovery, inflammatory response, and fecal microbiota in patients undergoing colorectal surgery: a prospective, randomized clinical trial. Biosci Microbiota Food Health 2016; 35: 77-87.
98. Polakowski CB, Kato M, Preti VB, et al. Impact of the preoperative use of synbiotics in colorectal cancer patients: a prospective, randomized, double-blind, placebo-controlled study. Nutrition 2019; 58: 40-6.
99. Horvath K, Papadimitriou JC, Rabsztyn A, et al. Gastrointestinal abnormalities in children with autistic disorder. J Pediatr 1999; 135: 559-63.
100. Yokoyama Y, Nishigaki E, Abe T, et al. Randomized clinical trial of the effect of perioperative synbiotics versus no synbiotics on bacterial translocation after oesophagectomy. Br J Surg 2014; 101: 189-99.
101. Anderson ADG, McNaught CE, Jain PK, et al. Randomised clinical trial of synbiotic therapy in elective surgical patients. Gut 2004; 53: 241-5.
102. Krebs B. Prebiotic and synbiotic treatment before colorectal surgery – randomised double blind trial. Coll Antropol 2016; 40: 35-40.
103. Zhu H, Ren Z, Zang Y, et al. Effects of microecological preparations on obese patients after bariatric surgery: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2020; 2020: 8724546.
104. Karbaschian Z, Mokhtari Z, Pazouki A, et al. Probiotic supplementation in morbid obese patients undergoing one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB) surgery: a randomized, double-blind, placebo-controlled, clinical trial. Obes Surg 2018; 28: 2874-85.
105. Roussel E, Brasse-Lagnel C, Tuech JJ, et al. Influence of probiotics administration before liver resection in patients with liver disease: a randomized controlled trial. World J Surg 2022; 46: 656-65.
106. Xu Q, Xu P, Cen Y, et al. Effects of preoperative oral administration of glucose solution combined with postoperative probiotics on inflammation and intestinal barrier function in patients after colorectal cancer surgery. Oncol Lett 2019; 18: 694-8.
107. Żywienie w zaburzeniach mikrobioty jelitowej. Stachowska E (ed.). PZWL Wydawnictwo Lekarskie, Warszawa 2021.
108. Vernocchi P, Del Chierico F, Putignani L, et al. Gut microbiota metabolism and interaction with food components. Int J Mol Sci 2020; 21: 3688.
109. Muscogiuri G, Cantone E, Cassarano S, et al. Gut microbiota: a new path to treat obesity. Int J Obes Suppl 2019; 9: 10-9.
110. Perna S, Ilyas Z, Giacosa A, et al. Is probiotic supplementation useful for the management of body weight and other anthropometric measures in adults affected by overweight and obesity with metabolic related diseases? A systematic review and meta-analysis. Nutrients 2021; 13: 666.
111. Torres B, Sánchez MC, Virto L, et al. Use of probiotics in preventing and treating excess weight and obesity. A systematic review. Obes Sci Pract 2024; 10: e759.
112. Abdalqadir N, Adeli K. GLP-1 and GLP-2 orchestrate intestine integrity, gut microbiota, and immune system crosstalk. Microorganisms 2022; 10: 2061.
113. Zhang Z, Liang X, Lv Y, et al. Evaluation of probiotics for improving and regulation metabolism relevant to type 2 diabetes in vitro. J Funct Foods 2020; 64: 103664.
114. Ayesha IE, Monson NR, Klair N, et al. Probiotics and their role in the management of type 2 diabetes mellitus (short-term versus long-term effect): a systematic review and meta-analysis. Cureus 2023; 15: e46741.
115. Rittiphairoj T, Pongpirul K, Janchot K, et al. Probiotics contribute to glycemic control in patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Adv Nutr 2021; 12: 722-34.
116. Khan S, Ahmad F, Khalid N, et al. Applications of strain-specific probiotics in the management of cardiovascular diseases: a systemic review. Mol Nutr Food Res 2024; 68: 2300675.
117. Dixon A, Robertson K, Yung A, et al. Efficacy of probiotics in patients of cardiovascular disease risk: a systematic review and meta-analysis. Curr Hypertens Rep 2020; 22: 74.
118. Depommier C, Everard A, Druart C, et al. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nat Med 2019; 25: 1096-103.
119. Ashrafian F, Keshavarz Azizi Raftar S, Shahryari A, et al. Comparative effects of alive and pasteurized Akkermansia muciniphila on normal diet-fed mice. Sci Rep 2021; 11: 17898.
120. Cani PD, Depommier C, Derrien M, et al. Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms. Nat Rev Gastroenterol Hepatol 2022; 19: 625-37.
121. Zhou Q, Zhang Y, Wang X, et al. Gut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project. Nutr Metab 2020; 17: 90.
122. Mruk-Mazurkiewicz H, Kulaszyńska M, Czarnecka W, et al. Insights into the mechanisms of action of Akkermansia muciniphila in the treatment of non-communicable diseases. Nutrients 2024; 16: 1695.
123. Segers A, de Vos WM. Mode of action of Akkermansia muciniphila in the intestinal dialogue: role of extracellular proteins, metabolites and cell envelope components. Microbiome Res Rep 2023; 2: 6.
124. European Commission. Novel Food [Internet]. Available at: https://food.ec.europa.eu/safety/novel-food_en
125. EFSA Scientific Committee. Introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA ‐ Opinion of the Scientific Committee. EFSA J 2007; 5: 587.
126. EFSA Panel, Koutsoumanis K, Allende A, et al. The list of QPS status recommended biological agents for safety risk assessments carried out by EFSA [Internet]. Zenodo; 2021. Available at https://zenodo.org/records/4428353
127. Rannikko J, Holmberg V, Karppelin M, et al. Fungemia and other fungal infections associated with use of Saccharomyces boulardii probiotic supplements. Emerg Infect Dis 2021; 27: 2090-6.
128. Cogo E, Elsayed M, Liang V, et al. Probiotics evaluation in oncological surgery: a systematic review of 36 randomized controlled trials assessing 21 diverse formulations. Curr Oncol 2021; 28: 5192-214.
129. Didari T, Solki S, Mozaffari S, et al. A systematic review of the safety of probiotics. Expert Opin Drug Saf 2014; 13: 227-39.
Copyright: © 2024 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.