eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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abstract:
Case report

Microinvasive lobular carcinoma arising in a benign phyllodes tumour – a short report and brief review of the literature

Thomas Butters
1
,
Lynsey Williams
1
,
Charanjit Kaur
1
,
Zoltan Szollosi
1

  1. St. George’s Hospital, London, United Kingdom
Pol J Pathol 2024; 75 (3)
DOI: https://doi.org/10.5114/pjp.2024.142085
Online publish date: 2024/08/08
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Lobular carcinoma in situ (LCIS) with microinvasion is a rare entity which is rarely reported in the literature. We describe a case of microinvasive LCIS following excision of a fibroepithelial lesion. The lesion was graded as U3 and M3 on ultrasonography and mammography respectively, and on core needle biopsy was described as a fibroepithelial lesion with ‘unusual features’. Microscopic examination revealed a fibroepithelial lesion focally colonised by florid E-cadherin negative LCIS with multiple foci of microinvasive classical lobular carcinoma, which lacked a myoepithelial layer on CK5 and S100 staining.
keywords:

microinvasive, lobular, carcinoma, breast, phyllodes
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