Molecular factors involved in skin dryness in diabetic patients

Joanna Narbutt; Igor Bednarski; Aleksandra Lesiak

doi:10.5114/dr.2016.60627

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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3/2016
vol. 103

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abstract:

Review paper

Molecular factors involved in skin dryness in diabetic patients

Joanna Narbutt

,

Igor A. Bednarski

,

Aleksandra Lesiak

Przegl Dermatol 2016, 103, 222–226

DOI: https://doi.org/10.5114/dr.2016.60627

Online publish date: 2016/06/28

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Diabetes is a chronic systemic disease affecting 8.3% of the general population, thus constituting an important clinical and financial problem for healthcare systems throughout the world. Complications of diabetes damage both many internal organs and skin. Skin complications of diabetes can anticipate its clinical symptoms. Diabetic skin, irritated and dry in many cases, is susceptible to skin infections. However, there is little known about molecular changes in skin in diabetes. Many studies are concentrated on epidermal barrier damage, dysfunction of epidermis integrity and dysfunction of sebaceous glands. Another complex problem is skin care in diabetic patients. A profound understanding of cellular-level processes in diabetes could lead to the discovery of new therapy efficacy markers and new skin care products.

keywords:

Molecular factors involved in skin dryness in diabetic patients

Joanna Narbutt , Igor A. Bednarski , Aleksandra Lesiak

diabetes, dry skin, emollients

Joanna Narbutt

,

Igor A. Bednarski

,

Aleksandra Lesiak