Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms

Ieva Adomaite; Evelina Gorbikova; Monika Miskinyte; Audrone Eidukaite; Asta Miskiniene; Odilija Rudzeviciene

doi:10.5114/ada.2022.124741

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2023
vol. 40

Send email

Copy url:

abstract:

Original paper

Molecular peanut sensitization patterns in Lithuanian children with suspected allergic symptoms

Ieva Adomaite

¹

,

Evelina Gorbikova

²

,

Monika Miskinyte

³

,

Audrone Eidukaite

²

,

Asta Miskiniene

³

,

Odilija Rudzeviciene

¹

Clinic of Children’s Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Centre for Innovative Medicine, Vilnius, Lithuania
JSC “In Novum“, Vilnius, Lithuania

Adv Dermatol Allergol 2023; XL (1): 107-110

DOI: https://doi.org/10.5114/ada.2022.124741

Online publish date: 2023/02/27

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Adomaite I, Gorbikova E, Miskinyte M, Eidukaite A, Miskiniene A, Rudzeviciene O. Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2023;40(1):107-110. doi:10.5114/ada.2022.124741.

APA

Adomaite, I., Gorbikova, E., Miskinyte, M., Eidukaite, A., Miskiniene, A.,  & Rudzeviciene, O. (2023). Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 40(1), 107-110. https://doi.org/10.5114/ada.2022.124741

Chicago

Adomaite, Ieva, Evelina Gorbikova, Monika Miskinyte, Audrone Eidukaite, Asta Miskiniene,  and Odilija Rudzeviciene. 2023. "Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 40 (1): 107-110. doi:10.5114/ada.2022.124741.

Harvard

Adomaite, I., Gorbikova, E., Miskinyte, M., Eidukaite, A., Miskiniene, A.,  and Rudzeviciene, O. (2023). Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 40(1), pp.107-110. https://doi.org/10.5114/ada.2022.124741

MLA

Adomaite, Ieva et al. "Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 40, no. 1, 2023, pp. 107-110. doi:10.5114/ada.2022.124741.

Vancouver

Adomaite I, Gorbikova E, Miskinyte M, Eidukaite A, Miskiniene A, Rudzeviciene O. Molecular peanut sensitization patterns in Lithuanian
children with suspected allergic symptoms. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2023;40(1):107-110. doi:10.5114/ada.2022.124741.

Introduction:
There are no in-depth studies describing the peanut sensitization molecular patterns in Lithuanian children.

Aim:
To investigate the age-related patterns of molecular peanut sensitization profiles in Lithuanian children with suspected allergic symptoms.

Material and methods:
We performed a retrospective analysis of peanut sensitization profiles in 576 Lithuanian children with possible allergic symptoms. Patient data were categorized according to age groups: 0–2, 3–6, 7–12, and 13–18 years. Specific immunoglobulin E levels to peanut molecular components: Ara h 1, Ara h 2, Ara h 3, Ara h 6, Ara h 8, Ara h 9, Ara h 15, and birch major allergen component Bet v 1 were analyzed.

Results:
Sensitization to at least one peanut protein was observed in 148 (25.7%) children. In children aged ≤ 2 years, most children were sensitized to Ara h 1 – 11 (12.1%). In children aged from 3 to 6 years, the sensitization to Ara h 1 remained the most prevalent in 40 (16.6%) children. The most prevalent sensitization in children aged from 7 to 12 years was to Ara h 8 in 39 (24.5%) of them. In children aged ≥ 13 years, Ara h 8 remained the most prevalent sensitizer in 21 (24.7%) of them.

Conclusions:
One-fourth of children with suspected allergic symptoms are sensitized to at least one peanut molecular component in Lithuania. Infants and preschool children are most commonly sensitized to seed storage proteins, while school-age children to Ara h 8 allergen.

keywords:

Molecular peanut sensitization patterns in Lithuanian children with suspected allergic symptoms

Ieva Adomaite 1 , Evelina Gorbikova 2 , Monika Miskinyte 3 , Audrone Eidukaite 2 , Asta Miskiniene 3 , Odilija Rudzeviciene 1

component-resolved diagnostics, peanut allergy, food allergy, specific immunoglobulin E

Ieva Adomaite

¹

,

Evelina Gorbikova

²

,

Monika Miskinyte

³

,

Audrone Eidukaite

²

,

Asta Miskiniene

³

,

Odilija Rudzeviciene

¹