eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

without publication fees
3/2011
vol. 62
 
Share:
Send email
Share:
abstract:

Morphometric distinction of signet-ring cell adenocarcinoma cells from foamy macrophages in gastric endoscopic biopsies

Andrzej Kram
,
Marieta Peychewa
,
Svetlana Bachurska
,
Wenancjusz Domagala

POL J PATHOL 2011; 3: 145-147
Online publish date: 2011/11/17
View full text Get citation
 
Aims : To distinguish signet-ring cancer cells from foamy macrophages in the small gastric endoscopic biopsies using objective morphometric measurements of nuclei.

Material and methods : Using computerized image analysis, the mean nuclear area, length, breadth, perimeter and roundness were analyzed in histological sections of ten gastric endoscopic biopsies with signet-ring cell adenocarcinoma and four benign lesions with numerous foamy macrophages.

Results : Nuclei of signet-ring cell adenocarcinoma were significantly bigger than nuclei of foamy macrophages. Mean nuclear area (34.25 μm2 for carcinoma cells vs. 25.41 μm2 for macrophages) and mean nuclear breadth (5.82 μm vs. 4.99 μm, respectively) differed significantly (P < 0.05), whereas the remaining parameters did not.

Conclusion : Nuclear morphometry can distinguish foamy macrophages from signet-ring cell adenocarcinoma cells in endoscopic gastric biopsies.
keywords:

stomach cancer, signet-ring cell adenocarcinoma, macrophages, morphometry, gastric biopsy
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.