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Review paper

NECROBIOSIS LIPOIDICA – A RARE DISEASE CAUSING THERAPEUTIC DIFFICULTIES: A REVIEW OF AVAILABLE AND POTENTIAL TREATMENTS

Dominika Dzik
1
,
Paweł Jerczyński
1
,
Jakub Cecot
1
,
Konrad Zarzecki
2
,
Miłosz Mandryk
2

  1. J. Mikulicz-Radecki University Clinical Hospital, Wrocław, Poland
  2. 4th Military Clinical Hospital, Wrocław, Poland
Health Prob Civil.
Online publish date: 2024/12/06
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- Dzik et al.pdf  [0.53 MB]
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1. Li Pomi F, Motolese A, Paganelli A, Vaccaro M, Alberico Motolese, Borgia F. Shedding light on photodynamic therapy in the treatment of necrobiosis lipoidica: a multicenter real-life experience. International Journal of Molecular Sciences. 2024; 25(7): 3608. https://doi.org/10.3390/ijms25073608
2. Blevins M. Atypical ulcerative necrobiosis lipoidica diabeticorum: a case study. The International Journal of Lower Extremity Wounds. 2021; 22(1): 185-189. https://doi.org/10.1177/1534734621999269
3. Pourang A, Sivamani RK. Treatment-resistant ulcerative necrobiosis lipoidica in a diabetic patient responsive to ustekinumab. Dermatology Online Journal. 2019; 25(8): 11. https://doi.org/10.5070/d3258045141
4. Elzaouk E, Bourlond F, Scrivener Y, Cribier B. Post-traumatic ulcerated and chronic necrobiosis lipoidica of the elbow: a new entity?. Annales de Dermatologie et de Vénéréologie. 2023; 150(3): 185-8. https://doi.org/10.1016/j.annder.2023.03.005
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6. Gutierrez D, Steuer AB, Marji JS, Cindy Bae YS. Treatment of necrobiosis lipoidica with pulsed dye laser. Dermatologic Surgery. 2020; 46(11): 1468-70. https://doi.org/10.1097/dss.0000000000002097
7. Rajabi-Estarabadi A, Aickara DJ, Hirsch M, Williams NM, Maranda EL, Van Badiavas E. Laser and light therapies for the treatment of necrobiosis lipoidica. Lasers in Medical Science. 2020; 36(3): 497–506. https://doi.org/10.1007/s10103-020-03147-3
8. Nihal A, Caplan AS, Rosenbach M, Damsky W, Mangold AR, Shields BE. Treatment options for necrobiosis lipoidica: a systematic review. International Journal of Dermatology. 2023; 62(12): 1529–37. https://doi.org/10.1111/ijd.16856
9. Damsky W, Singh K, Galan A, King B. Treatment of necrobiosis lipoidica with combination Janus kinase inhibition and intralesional corticosteroid. JAAD Case Reports. 2020; 6(2): 133-5. https://doi.org/10.1016/j.jdcr.2019.11.016
10. Shrestha S, Spierings N, Marahatta S. Necrobiosis lipoidica: a case report with dermoscopic review. Clinical Case Reports. 2021; 9(3): 1171–4. https://doi.org/10.1002/ccr3.3713
11. Quintana‐Castanedo L, Recarte‐Marín L, Pérez‐Jerónimo L, Conde‐Montero E, Cueva‐Dobao P. Ulcerative necrobiosis lipoidica diabeticorum successfully treated with topical sevoflurane and punch grafting. International Wound Journal. 2019; 16(5): 1234–6. https://doi.org/10.1111/iwj.13179
12. Arnet L, Erfurt‐Berge C. Effect of abrocitinib in a patient with extensive necrobiosis lipoidica. JEADV Journal of the European Academy of Dermatology and Venereology. 2023; 37(10): e1208-e1210. https://doi.org/10.1111/jdv.19189
13. McPhie ML, Swales WC, Gooderham M. Improvement of granulomatous skin conditions with tofacitinib in three patients: a case report. SAGE Open Medical Case Reports. 2021; 9. https://doi.org/10.1177/2050313x211039477
14. Erfurt‐Berge C, Sticherling M. Successful treatment of ulcerative necrobiosis lipoidica with janus kinase inhibitor. Journal of the European Academy of Dermatology and Venereology. 2020; 34(7): e331-e333. https://doi.org/10.1111/jdv.16297
15. Janßen S, Jansen TM. Ulcerated necrobiosis lipoidica successfully treated with tofacitinib. International Journal of Dermatology. 2021; 61(6): 739–41. https://doi.org/10.1111/ijd.15960
16. Kumari Sandhu V, Alavi A. The role of anti-tumour necrosis factor in wound healing: a case report of refractory ulcerated necrobiosis lipoidica treated with adalimumab and review of the literature. SAGE Open Medical Case Reports. 2019; 7. https://doi.org/10.1177/2050313x19881594
17. Fertitta L, Vignon-Pennamen MD, Frazier A, Guibal F, Caumes E, Bagot M, et al. Necrobiosis lipoidica with bone involvement successfully treated with infliximab. Rheumatology. 2019; 58(9): 1702–3. https://doi.org/10.1093/rheumatology/kez055
18. Gibson RS, Salian P, Beckles A, Stavert R, Tahan S, Kimball AB, et al. Treatment of necrobiosis lipoidica with secukinumab (Cosentyx): a case series. International Journal of Dermatology. 2023; 62(9): 1198–201. https://doi.org/10.1111/ijd.16780
19. Burns E, Ukoha U, Chan A. Necrobiosis lipoidica with rapid response to doxycycline. Pediatric Dermatology. 2020; 37(5): 981–2. https://doi.org/10.1111/pde.14295
20. Fulgencio-Barbarin J, Conde Montero E. Sequential punch grafting for treatment of ulcerative necrobiosis lipoidica. Journal of Tissue Viability. 2022; 31(2): 560-561. https://doi.org/10.1016/j.jtv.2022.04.006
21. Baccarani A, De Maria F, Pappalardo M, Pedone A, De Santis G. Necrobiosis lipoidica affecting the leg: what is the best treatment in a patient with very high aesthetic demand?. Plastic and Reconstructive Surgery – Global Open. 2020; 8(7): e3000. https://doi.org/10.1097/gox.0000000000003000
22. Hrin ML, Oscherwitz M, Jorizzo JL, Feldman SR, Huang WW. Evaluation of pentoxifylline in the treatment of necrobiosis lipoidica: outcomes in 10 patients. International Journal of Dermatology. 2024; 63(3): 390-392. https://doi.org/10.1111/ijd.17037
Copyright: © 2024 Pope John Paul II State School of Higher Education in Biała Podlaska. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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