Nephrotic syndrome and neoplasia: our experience and review of the literature

Małgorzata Wągrowska-Danilewicz; Marian Danilewicz

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

1/2011
vol. 62

Send email

Copy url:

abstract:

Nephrotic syndrome and neoplasia: our experience and review of the literature

Małgorzata Wągrowska-Danilewicz

,

Marian Danilewicz

Pol J Pathol 2011; 1: 12–18

Online publish date: 2011/05/11

View full text Get citation

The glomerular lesion of paraneoplastic nephrotic syndrome usually presents as membranous nephropathy, minimal change disease or membranoproliferative glomerulonephritis. We present six cases of paraneoplastic nephrotic syndrome. Four cases were associated with epithelial malignancies (lung, gastric and colon cancer), and two cases with lymphoproliferative malignancies (Hodgkin’s lymphoma and chronic lymphocytic leukemia). On the basis of light microscopy, immunofluorescence study and electron microscopy, membranous nephropathy, minimal change disease, and membranoproliferative glomerulopathy were established. We concluded, that the search for malignancy is warranted in patients over the age of 55 presenting with nephrotic syndrome, particularly in cases of membranous nephropathy.

keywords:

Nephrotic syndrome and neoplasia: our experience and review of the literature

Małgorzata Wągrowska-Danilewicz , Marian Danilewicz

nephrotic syndrome, malignancy, glomerulonephritis, cancer

Małgorzata Wągrowska-Danilewicz

,

Marian Danilewicz