eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
3-4/2005
vol. 30
 
Share:
Send email
Share:
abstract:

Nijmegen breakage syndrome. Diagnostic difficulties in primary immunodeficiency

Aleksandra Szczawińska-Popłonyk
,
Anna Popiel
,
Anna Bręborowicz
,
Barbara Pietrucha
,
Ewa Bernatowska

(Centr Eur J Immunol 2005; 30 (3-4): 83-88)
Online publish date: 2006/10/10
View full text Get citation
 
Recurrent respiratory tract infections are one of the most common manifestations of primary immunodeficiencies in children. The diagnosis is often based on the results of broad differential diagnostic procedures. These should include not only evaluation of the immune system and identification of the infectious agents, but also clinical evaluation which should take into consideration variable manifestations from different organs and systems which together comprise the syndrome. The aim of this study is to present both the pathogenetic aspects of Nijmegen breakage syndrome, with particular emphasis on immunodeficiency and clinical manifestations and also of difficulties accompanying diagnostic procedures. The material of the paper consists of a presentation of the case of a nine-year old girl with Nijmegen breakage syndrome, manifesting symptoms of advanced respiratory disease. Diagnosis of the primary immunodeficiency syndrome requires the standards used in diagnosis and therapy of the immune system.
keywords:

Nimegen breakage syndrome, immunodeficiency, children
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.