The impact of erythropoietin treatment of anemia on the effectiveness of chemotherapy: analysis of selected parameters and clinical data

Marek Pawlicki; Jan Kulpa; Beata Żuchowska; Urszula Rychlik; Zofia Stasik

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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6/2005
vol. 9

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abstract:

The impact of erythropoietin treatment of anemia on the effectiveness of chemotherapy: analysis of selected parameters and clinical data

Marek Pawlicki

,

Jan Kulpa

,

Beata Żuchowska

,

Urszula Rychlik

,

Zofia Stasik

Współcz Onkol (2005); 9: 237-240

Online publish date: 2005/09/06

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Anemia is a frequent complication of cancer. It may be exclusively a consequence of the presence of malignant disease itself (cancer-related anemia; CRA) or a result of cancer treatment methods, radiotherapy and/or cytotoxic chemotherapy (radio- and chemotherapy-induced anemia). The aim of the presented study was to evaluate effectiveness of anemia treatment with erythropoietin. Pivotal groups of 68 patients were treated with erythropoietin due to cancer-related anemia occurring before or in the course of chemotherapy. The percentage of patients (52.4%) with an observed increase in the hemoglobin level (at least by 2 g/dl) was lower than data published in other studies. The treatment was well tolerated. Only in one case (1.47%) it was necessary to discontinue treatment because of deep vein thrombosis. The effectiveness of erythropoietin treatment seems to depend on the patients\' condition, pretreatment hemoglobin level (<8.5 g/dl) and duration of chemotherapy.

keywords:

The impact of erythropoietin treatment of anemia on the effectiveness of chemotherapy: analysis of selected parameters and clinical data

Marek Pawlicki , Jan Kulpa , Beata Żuchowska , Urszula Rychlik , Zofia Stasik

anemia, erythropoietin, chemotherapy effectiveness

Marek Pawlicki

,

Jan Kulpa

,

Beata Żuchowska

,

Urszula Rychlik

,

Zofia Stasik