Ocena wybranych wykładników odpowiedzi immunologicznej u dzieci z objawami zapalenia części pośredniej błony naczyniowej

Purpose
The purpose of this study was to estimate markers of immunological response in the blood of children with intermediate uveitis

Material and methods
: The records of 13 children (26 eyes), aged 10-17 years, with idiopathic intermediate uveitis were reviewed. In all cases indicators of inflammation and immunological response parameters were analyzed during the active stage of the disease.

Results
: In almost all patients ((90%) with intermediate uveitis disturbances in the level and activity of lymphocyte system, were detected. There were also nonspecific changes in immunoglobulins level in all patients, in 31% in more then one class of immunoglobulins. Chemiluminescence of phagocytic cells were reduced in more than 50% of children, and increase in their phagocytic activity was observed in 62% of patients. Circulating immune complexes were present in 50% of cases.

Conclusions
The study presents data supporting the theory of autoimmunological background of the intermediate uveitis.