eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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1/2008
vol. 25
 
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abstract:

Case report
Melkersson-Rosenthal syndrome. Case report and review of the literature

Michał Sobjanek
,
Izabela Żelazny
,
Adam Włodarkiewicz
,
Roman Nowicki
,
Igor Michajłowski

Post Dermatol Alergol 2008; XXV, 1: 43–47
Online publish date: 2008/02/19
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Melkersson-Rosenthal syndrome is characterized by a triad of signs: oedema of the face and lips, recurrent peripheral facial nerve paralysis, and fissured tongue (lingua plicata). Monosymptomatic or oligosymptomatic forms of Melkersson-Rosenthal syndrome are common. Aetiology is still unclear. Genetic, autoimmune and infectious factors have been proposed. The authors present a case of a 40-year-old man with Melkersson-Rosenthal syndrome treated with good effect by combination therapy consisting of intralesional injection of triamcinolone, and oral dapsone. The authors also review the literature of clinical presentation and current treatment of this rare syndrome.
keywords:

Melkersson-Rosenthal syndrome, cheiltis granulomatosa, orofacial granulomatosis, treatment
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