Original article<br>Distribution of HBV genotypes in Poland

Magdalena Świderska; Małgorzata Pawłowska; Włodzimierz Mazur; Krzysztof Tomasiewicz; Krzysztof Simon; Anna Piekarska; Marta Wawrzynowicz-Syczewska; Jerzy Jaroszewicz; Paweł Rajewski; Ewelina Zasik; Elżbieta Murias-Bryłowska; Anna Pniewska; Waldemar Halota; Robert Flisiak

doi:10.5114/ceh.2015.51372

eISSN: 2449-8238
ISSN: 2392-1099

Clinical and Experimental Hepatology

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abstract:

Original article
Distribution of HBV genotypes in Poland

Magdalena Świderska

,

Małgorzata Pawłowska

,

Włodzimierz Mazur

,

Krzysztof Tomasiewicz

,

Krzysztof Simon

,

Anna Piekarska

,

Marta Wawrzynowicz-Syczewska

,

Jerzy Jaroszewicz

,

Paweł Rajewski

,

Ewelina Zasik

,

Elżbieta Murias-Bryłowska

,

Anna Pniewska

,

Waldemar Halota

,

Robert Flisiak

Clinical and Experimental Hepatology 2015; 1: 1–4

DOI: https://doi.org/10.5114/ceh.2015.51372

Online publish date: 2015/04/30

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Aim of the study: To identify distribution of HBV genotypes in particular regions of Poland.

Material and methods: The study included 270 treatment-naïve, HBV-infected individuals, enrolled in 7 centers of Poland. HBV genotyping was performed in 243 of them with the INNO-LiPA HBV Genotyping assay (Innogenetics).

Results: Genotype A present in 2/3 patients was demonstrated as the most predominant in Poland. It was followed by D (20%), H (5%) and mixed A + D (5%). Remaining patients were infected with genotype F, mixed D + G, A + C or D + F. Analysis of distribution demonstrated regional differences, with a higher rate of genotype D prevalence (about 30%) in the eastern (Białystok and Lublin) and south-western (Wrocław) parts compared to other regions, where the prevalence rate was below 15%. The highest prevalence of genotype A (exceeding 80%) was observed in central Poland (Bydgoszcz, Łódź).

Conclusions: The presented data reveal the current distribution of HBV genotypes across Poland, which is the first and the largest such epidemiological analysis.

keywords:

Original articleDistribution of HBV genotypes in Poland

Magdalena Świderska , Małgorzata Pawłowska , Włodzimierz Mazur , Krzysztof Tomasiewicz , Krzysztof Simon , Anna Piekarska , Marta Wawrzynowicz-Syczewska , Jerzy Jaroszewicz , Paweł Rajewski , Ewelina Zasik , Elżbieta Murias-Bryłowska , Anna Pniewska , Waldemar Halota , Robert Flisiak

HBV, epidemiology, hepatitis, genotypes

Original article
Distribution of HBV genotypes in Poland