Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case

Małgorzata Wiszniewska; Andrzelika Domagalska; Paweł Wiszniewski

doi:10.5114/ppn.2020.103636

eISSN: 2720-5371
ISSN: 1230-2813

Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii

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vol. 29

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Opis przypadku

Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case

Małgorzata Wiszniewska

^{1, 2}

,

Andrzelika Domagalska

²

,

Paweł Wiszniewski

³

Stanisław Staszic University of Applied Sciences, Faculty of Nursing, Piła, Poland
Specialist Hospital, Neurological Department with Stroke Unit, Piła, Poland
Hematological Department, Ars Medical Hospital, Piła, Poland

DOI: https://doi.org/10.5114/ppn.2020.103636

Data publikacji online: 2021/01/30

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AMA

Wiszniewska M, Domagalska A, Wiszniewski P. Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii. 2020;29(4):246-249. doi:10.5114/ppn.2020.103636.

APA

Wiszniewska, M., Domagalska, A.,  & Wiszniewski, P. (2020). Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, 29(4), 246-249. https://doi.org/10.5114/ppn.2020.103636

Chicago

Wiszniewska, Małgorzata, Andrzelika Domagalska,  and Paweł Wiszniewski. 2020. "Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case". Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii 29 (4): 246-249. doi:10.5114/ppn.2020.103636.

Harvard

Wiszniewska, M., Domagalska, A.,  and Wiszniewski, P. (2020). Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, 29(4), pp.246-249. https://doi.org/10.5114/ppn.2020.103636

MLA

Wiszniewska, Małgorzata et al. "Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case." Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, vol. 29, no. 4, 2020, pp. 246-249. doi:10.5114/ppn.2020.103636.

Vancouver

Wiszniewska M, Domagalska A, Wiszniewski P. Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii. 2020;29(4):246-249. doi:10.5114/ppn.2020.103636.

Metryki PlumX:

Purpose
Essential thrombocythemia (ET) is characterised by an overproduction of platelets in the absence of the states that induce secondary thrombopoiesis. The most common and significant complication of ET is arterial and venous thrombosis. The most serious complication of ET is stroke.

Case description
We present a patient with a stroke that started with an unusual symptom – syncope, successfully treated with recombinant tissue plasminogen activator alteplase. Three years after the stroke, the patient lives an independent life but with cerebellar-stem symptoms. Further long-term treatment is supervised by a haematologist.

Comment
Syncope in ET may be the first sign of stroke. To assess brainstem and cerebellar stroke, magnetic resonance imaging should be performed. In ET, thrombolytic treatment of ischemic stroke may be a life-saving treatment. Long-term treatment involving a platelet-lowering medication, along with anti-aggregation drugs, is necessary to treat stroke patients with ET. Females with ET who have suffered from a stroke should not use oral contraception.

Orthostatic syncope in a young woman with essential thrombocythemia found to be an initial sign of ischemic stroke – therapeutic concerns. Unusual case

Małgorzata Wiszniewska 1, 2 , Andrzelika Domagalska 2 , Paweł Wiszniewski 3

Małgorzata Wiszniewska

^{1, 2}

,

Andrzelika Domagalska

²

,

Paweł Wiszniewski

³