eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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3/2021
vol. 16
 
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abstract:
Review paper

Outcomes of percutaneous cholecystostomy in elderly patients: a systematic review and meta-analysis

George Markopoulos
1
,
Francesk Mulita
1
,
Dimitris Kehagias
1
,
Stylianos Tsochatzis
1
,
Charalampos Lampropoulos
1
,
Ioannis Kehagias
1

  1. Department of Surgery, General University Hospital of Patras, Patras, Greece
Gastroenterology Rev 2021; 16 (3): 188–195
DOI: https://doi.org/10.5114/pg.2020.100658
Online publish date: 2020/11/05
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Introduction
Percutaneous cholecystostomy (PC) represents a management option to control sepsis in patients with acute cholecystitis, who are unable to tolerate surgery.

Aim
This review aimed to evaluate the outcomes of elderly patients treated with PC and compare it with emergent cholecystectomy.

Material and methods
An electronic search of the Embase, Medline Web of Science, and Cochrane databases was performed. Percutaneous cholecystostomy was used as the reference group, and weighted mean differences (WMD) were calculated for the effect of PC on continuous variables, and pooled odds ratios (POR) were calculated for discrete variables.

Results
There were 20 trials included in this review. Utilisation of PC was associated with significantly increased mortality (POR = 4.85; 95% CI: 1.02–7.30; p = 0.0001) and increased re-admission rates (POR = 2.95; 95% CI: 2.21–3.87; p < 0.0001).

Conclusions
This pooled analysis established that patients treated with PC appear to have increased mortality and readmission rates relative to those managed with cholecystectomy.

keywords:

percutaneous cholecystostomy, cholecystitis, elderly
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