Personalized medicine in oncology. New perspectives in management of gliomas

Justyna Gil; Izabela Laczmanska; Karolina A. Pesz; Maria M. Sasiadek

doi:10.5114/wo.2018.73872

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

Current issue Archive Contemporary Oncology

1/2018

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abstract:

Review paper

Personalized medicine in oncology. New perspectives in management of gliomas

Justyna Gil

,

Izabela Laczmanska

,

Karolina A. Pesz

,

Maria M. Sasiadek

Contemp Oncol (Pozn) 2018; 22 (1A): 1–2

DOI: https://doi.org/10.5114/wo.2018.73872

Online publish date: 2018/03/08

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Studies on genetic and epigenetic mechanisms of carcinogenesis have led to the discovery of crucial genetic events for many of particular malignancies. This was followed by invention of new therapeutic approaches based on molecular mechanisms underlying cancer development and progression that bears the name of personalised medicine. In the case of gliomas, ascertainment of genetic/epigenetic markers was the basis for re-classification of tumours that until now depended on histopathological analysis. This article reviews recent advances in personalised medicine and the new World Health Organisation classification of gliomas.

keywords:

Personalized medicine in oncology. New perspectives in management of gliomas

Justyna Gil , Izabela Laczmanska , Karolina A. Pesz , Maria M. Sasiadek

gliomas, epigenetic mechanisms of carcinogenesis, personalized medicine

Justyna Gil

,

Izabela Laczmanska

,

Karolina A. Pesz

,

Maria M. Sasiadek