Perspectives of melatonin usage in prophylaxis and treatment of postmenopausal osteoporosis

Beata Kos-Kudła; Bogdan Marek; Dariusz Kajdaniuk; Kinga Wołowska; Zofia Ostrowska

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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5/2003
vol. 2

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abstract:

Perspectives of melatonin usage in prophylaxis and treatment of postmenopausal osteoporosis

Beata Kos-Kudła

,

Bogdan Marek

,

Dariusz Kajdaniuk

,

Kinga Wołowska

,

Zofia Ostrowska

(Prz Menopauz 2003, 5: 43–46)

Online publish date: 2003/10/17

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Pathogenesis of osteoporosis is complicated, multifactorial, and is still not fully recognized. Results of below presented study suggest that among factors determining pathogenesis of this disease, not only estrogen deficiency in postmenopausal period and many other well known hormonal, growth, immunological factors but also melatonin deficiency plays a substantial role. Many of recently published studies demonstrated that increased melatonin production may have protective effect against loss of bone mass in postmenopausal period.
We postulated that administration of melatonin could have a beneficial effect in prophylaxis and treatment of postmenopausal osteoporosis.

keywords:

Perspectives of melatonin usage in prophylaxis and treatment of postmenopausal osteoporosis

Beata Kos-Kudła , Bogdan Marek , Dariusz Kajdaniuk , Kinga Wołowska , Zofia Ostrowska

melatonin, menopause, osteoporosis

Beata Kos-Kudła

,

Bogdan Marek

,

Dariusz Kajdaniuk

,

Kinga Wołowska

,

Zofia Ostrowska