eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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4/2004
vol. 3
 
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abstract:

CYP19 gene polymorphism as the potential risk factor of endometrial cancer

Bartosz Kulig
,
Karolina Przybyłowska
,
Beata Smolarz
,
Krzysztof Szyłło
,
Andrzej Kulig
,
Hanna Romanowicz-Makowska

Prz Menopauz 2004; 4: 48–52
Online publish date: 2004/08/26
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The enzymatic P 450 complex is responsible for synthesis and metabolism of estrogens and progesteron. A strong relationship between polymorphism in the CYP 450 complex and enzyme activity has been observed in many articles. This article is a summary of available data, described influence polymorphism CYP 450 gene on endometrial cancer and other hormone – dependent cancers.
keywords:

polymorphism, CYP, endometrial cancer
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