eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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3/2020
vol. 15
 
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abstract:
Original paper

Postoperative supplementation of propionate and silicon dioxide in patients after total gastrectomy – preliminary report

Dorota Domagalska
1
,
Bartosz Grzechulski
1
,
Jacek Paszkowski
1
,
Mirosława Gałęcka
2
,
Tomasz Banasiewicz
1

  1. Department of General, Endocrine Surgery and Gastroenterological Oncology, Poznan University of Medical Science, Poznan, Poland
  2. Institute of Microecology, Poznan, Poland
Gastroenterology Rev 2020; 15 (3): 253–257
DOI: https://doi.org/10.5114/pg.2020.99040
Online publish date: 2020/09/19
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Introduction
Post-operative impairment of gastrointestinal tract function and metabolic consequences occur in patients after gastrectomy by Roux-en-Y method. Short-chain fatty acids and silicon dioxide may prove beneficial in the treatment of these conditions.

Aim
To evaluate a preparation containing propionic acid and silicon dioxide on the body weight, number of stools and their consistency (the Bristol scale), and pain and a feeling of gastric fullness after a meal, in patients after gastrectomy by Roux-en-Y method.

Material and methods
Measurements were performed at the beginning of the study, on day 7 and 14 of application (Co- lostop®; Miralex, 2 × 15 g/day).

Results and conclusions
Initially the average daily number of movements was 10/day, after the therapy it was 3.8/day. At the beginning of the study, 3 patients described their faeces as type 6 and two as type 7 on the Bristol scale. After supplementa- tion, 3 patients described stool consistency as type 5, and two as type 4. Initially, patients rated their pain at 3.4/10 on average, the stomach fullness as 4.6/10. At the end of the study, 3 patients did not feel any pain, while others reported pain at 1/10. Four patients described their feeling of gastric fullness as 1/10, and 1 no longer observed this feeling. Patients disclaimed any adverse effects, and satisfaction after therapy reached 9–10/10 points. Patients’ body weight did not change significantly. An improvement in standard diet tolerance was observed. Despite the limited study group, clinical benefits of the supplementation were observed.

keywords:

gastrectomy, silicon dioxide, propionate, diarrhea, surgery
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