Potential etiological factors in frontal fibrosing alopecia

Magdalena Maciejewska; Joanna Czuwara; Natalia Dąbrowska; Małgorzata Olszewska; Lidia Rudnicka

doi:10.5114/dr.2022.126602

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2022
vol. 109

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abstract:

Review article

Potential etiological factors in frontal fibrosing alopecia

Magdalena Maciejewska

¹

,

Joanna Czuwara

¹

,

Natalia Dąbrowska

¹

,

Małgorzata Olszewska

¹

,

Lidia Rudnicka

¹

Department of Dermatology, Medical University of Warsaw, Warsaw, Poland; Katedra i Klinika Dermatologiczna, Warszawski Uniwersytet Medyczny, Warszawa, Polska

Dermatol Rev/Przegl Dermatol 2022, 109, 427-436

DOI: https://doi.org/10.5114/dr.2022.126602

Online publish date: 2023/04/21

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Frontal fibrosing alopecia is a variant of lichen planus, leading to permanent hair loss from the frontal hairline. It occurs mainly in postmenopausal women, however, the role of hormonal factors in the pathogenesis of this type of alopecia has not been determined. The coexistence of frontal fibrosing alopecia and autoimmune diseases is observed, e.g., hypothyroidism, rheumatoid arthritis, vitiligo, polymyositis, systemic lupus erythematosus and discoid lupus erythematosus. Considering the possible role of genetic factors, research is underway to identify human leukocyte antigen (HLA) polymorphisms. One of the most studied factors is sunscreen, widely used in cosmetic products. The data available so far in this regard are controversial. Factors raising significant doubts include: the retrospective nature of the research, basing the collected data on the self-assessment of respondents and the lack of specification of the ingredients of these products. In the light of current data, sunscreen components cannot be considered as a factor playing a role in the pathogenesis of frontal fibrosing alopecia. Overestimation of the role of sunscreens in hair loss could lead to unjustified avoidance of their use and contribute to increased incidence of skin cancer.

keywords:

Potential etiological factors in frontal fibrosing alopecia

Magdalena Maciejewska 1 , Joanna Czuwara 1 , Natalia Dąbrowska 1 , Małgorzata Olszewska 1 , Lidia Rudnicka 1

frontal fibrosing alopecia, risk factors, titanium dioxide, UV filters

Magdalena Maciejewska

¹

,

Joanna Czuwara

¹

,

Natalia Dąbrowska

¹

,

Małgorzata Olszewska

¹

,

Lidia Rudnicka

¹