Premature ovarian failure

Katarzyna Jankowska

doi:10.5114/pm.2017.68592

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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2/2017
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abstract:

Review paper

Premature ovarian failure

Katarzyna Jankowska

Menopause Rev 2017; 16(2): 51-56

DOI: https://doi.org/10.5114/pm.2017.68592

Online publish date: 2017/06/30

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Premature ovarian failure (POF) is the term usually used to describe women aged younger than 40 years, who present with amenorrhoea, hypergonadotropic hypogonadism, and infertility. POF is a devastating diagnosis for reproductive-aged women. The clinical presentation is diverse, and several different disorders can lead to premature ovarian failure. POF has serious health consequences, including psychological distress, infertility, osteoporosis, autoimmune disorders, ischaemic heart disease, and increased risk of mortality. Hashimoto’s disease is the most frequent autoimmune disorder associated with premature ovarian failure. Management should be initiated immediately to prevent long-term consequences. Oestrogen therapy is the mainstay of management. Hormone therapy should be provided to eliminate symptoms of oestrogen deficiency.

keywords:

Premature ovarian failure

Katarzyna Jankowska

premature ovarian failure, infertility, menstrual disorders