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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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SCImago Journal & Country Rank
2/2011
vol. 113
 
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abstract:
Review paper

Prevention of posterior capsule opacification in experimental studies

Agnieszka Łukaszewska-Smyk
1
,
Józef Kałużny
1

  1. Klinika Chorób Oczu Collegium Medicum w Bydgoszczy Uniwersytetu Mikołaja Kopernika w Toruniu
Klinika Oczna 2011, 113 (2): 175-179
Online publish date: 2011/06/29
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The pharmaceuticals inhibiting proliferation of epithelium cells or causing their death were tested in experimental studies on PCO prevention. The following antymetabolites were tested: 5-fluorouracil, dounomycin, methotrexat and colchicine, epithelial antibodies against epithelial cells, toxins, hyperosmolar agents and heparin, indomethacine and lignocaine. Moreover, gene therapy with the use of apoptose genes was applied. None of the attempts to prevent PCO was useful for effective and safe clinical treatment.
keywords:

prevention of PCO, experimental studies, antymetabolites, toxins, gene therapy

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