Primary angiosarcoma of the vulva: report of a case misdiagnosed as a benign tumor

Simona Stolnicu; Cristian Podoleanu; Ildiko Orban; Octavian Stan; Bela Szabo

doi:10.5114/pjp.2021.109519

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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2/2021
vol. 72

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abstract:

Short report

Primary angiosarcoma of the vulva: report of a case misdiagnosed as a benign tumor

Simona Stolnicu

¹

,

Cristian Podoleanu

²

,

Ildiko Orban

³

,

Octavian Stan

⁴

,

Bela Szabo

⁵

Department of Pathology, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania
Department of Cardiology, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania
Department of Pathology, Emergency Hospital, Targu Mures, Romania
Department of Pathology, Emergency County Hospital Sfantu Gheorghe, Romania
Department of Gynecology and Obstetrics, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania

Pol J Pathol 2021; 72 (2): 167-169

DOI: https://doi.org/10.5114/pjp.2021.109519

Online publish date: 2021/09/30

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Primary vulvar angiosarcomas have a propensity for varied macroscopic and histologic appearance that initially may not suggest a vascular malignant neoplasm. Therefore, the rarity of the lesion and it’s morphologic diversity may contribute to the high rate of misdiagnosis. We present the case of a 43-year old patient with a primary vulvar lesion, initially misdiagnosed as an angiofibroma. Microscopic examination of the recurrence together with immunohistochemical profile were in favor on a poorly differentiated angiosarcoma. Early diagnoses can improve prognoses in angiosarcomas and, in the case of recurrences, as in the present case, may lead to changes in therapy.

keywords:

Primary angiosarcoma of the vulva: report of a case misdiagnosed as a benign tumor

Simona Stolnicu 1 , Cristian Podoleanu 2 , Ildiko Orban 3 , Octavian Stan 4 , Bela Szabo 5

primary angiosarcoma, vulva, morphology, immunohistochemistry, management

Simona Stolnicu

¹

,

Cristian Podoleanu

²

,

Ildiko Orban

³

,

Octavian Stan

⁴

,

Bela Szabo

⁵