Primary cutaneous lymphomas: diagnosis and treatment

Małgorzata Sokołowska-Wojdyło; Karolina Olek-Hrab; Katarzyna Ruckemann-Dziurdzińska

doi:10.5114/pdia.2015.54749

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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5/2015
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abstract:

Review paper

Primary cutaneous lymphomas: diagnosis and treatment

Małgorzata Sokołowska-Wojdyło

,

Karolina Olek-Hrab

,

Katarzyna Ruckemann-Dziurdzińska

Postep Derm Alergol 2015; XXXII (5): 368–383

DOI: https://doi.org/10.5114/pdia.2015.54749

Online publish date: 2015/10/29

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Primary cutaneous lymphomas (CLs) are a heterogeneous group of lymphoproliferative neoplasms, with lymphatic proliferation limited to the skin with no involvement of lymph nodes, bone marrow or viscera at the diagnosis. Cutaneous lymphomas originate from mature T-lymphocytes (65% of all cases), mature B-lymphocytes (25%) or NK cells. Histopathological evaluation including immunophenotyping of the skin biopsy specimen is the basis of the diagnosis, which must be complemented with a precise staging of the disease and identification of prognostic factors, to allow for the choice of the best treatment method as well as for the evaluation of the treatment results.

keywords:

Primary cutaneous lymphomas: diagnosis and treatment

Małgorzata Sokołowska-Wojdyło , Karolina Olek-Hrab , Katarzyna Ruckemann-Dziurdzińska

primary cutaneous lymphoma, mycosis fungoides, Sézary syndrome

Małgorzata Sokołowska-Wojdyło

,

Karolina Olek-Hrab

,

Katarzyna Ruckemann-Dziurdzińska