eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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3/2013
vol. 64
 
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abstract:

Primary mucoepidermoid carcinoma of the breast: a case report with immunohistochemical analysis and comparison with salivary gland mucoepidermoid carcinomas

Maria Heloisa Rached Palermo
,
Michelli Bárbara Pinto
,
Juliana Silva Zanetti
,
Alfredo Ribeiro-Silva

Pol J Pathol 2013; 64 (3): 210-215
DOI: https://doi.org/10.5114/pjp.2013.38141
Online publish date: 2013/10/21
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Mucoepidermoid carcinomas in mammary glands represent 0.3% of all breast tumors. Features of salivary gland mucoepidermoid carcinoma have been used in studies concerning mucoepidermoid carcinomas of the breast because both share similar morphologic and molecular features. We report a case of primary mucoepidermoid carcinoma of the breast with an immunohistochemistry staining panel. We verified that MUC5AC occurs in more than 50% of high-grade tumors, and MUC1 correlates with shorter disease-free survival. The comparative analysis of mucin profiles may provide further insights into the clinical behavior of these tumors.
keywords:

breast carcinoma, mucoepidermoid, immunohistochemistry, mucins, hormonal receptors
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