Profile of extrahepatic portal venous obstruction among children in Central India

Mayank Jain; Jenisha Jain; Gauri Rao Passi; Kamna Jain; Shikhar Jain

doi:10.5114/ceh.2017.71446

eISSN: 2449-8238
ISSN: 2392-1099

Clinical and Experimental Hepatology

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abstract:

Short report

Profile of extrahepatic portal venous obstruction among children in Central India

Mayank Jain

,

Jenisha Jain

,

Gauri Rao Passi

,

Kamna Jain

,

Shikhar Jain

Clin Exp HEPATOL 2017; 3, 4: 209-211

DOI: https://doi.org/10.5114/ceh.2017.71446

Online publish date: 2017/11/14

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Introduction: There is a paucity of data regarding the clinical profile of children with extrahepatic portal venous obstruction (EHPVO) from Central India.

Material and methods: Retrospective analysis of 30 children with EHPVO treated between 2002 and 2012.

Results: The median age of presentation was 12.5 years (range 5-14 years) and median duration of symptoms was 3.2 years (range 0.3-10 years). Home delivery was noted in 30 cases (100%), umbilical sepsis in 8 (27%) and history of cow dung application over the umbilical cord in 2 cases (6.7%). Twenty-two cases (73.4%) presented with upper gastrointestinal (GI) bleeding while 18 (60%) were referred for pancytopenia and/or hypersplenism. The patients underwent a median of 3.2 sessions of endoscopic therapy for varices. Most patients (19/30, 63.4%) dropped out of serial endotherapy due to the paucity of funds. Shunt surgery was performed in 7 patients.

Conclusions: Home delivery and umbilical sepsis are significant risk factors for EHPVO. Most patients present with GI bleeding and do well on endoscopic treatment/shunt surgery.

keywords:

Profile of extrahepatic portal venous obstruction among children in Central India

Mayank Jain , Jenisha Jain , Gauri Rao Passi , Kamna Jain , Shikhar Jain

portal hypertension, portal vein thrombosis, oesophageal varices

Mayank Jain

,

Jenisha Jain

,

Gauri Rao Passi

,

Kamna Jain

,

Shikhar Jain