eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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2/2019
vol. 18
 
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abstract:
Original paper

Prognostic factors influencing prognosis in early breast cancer patients

Safa Najafi
1
,
Masoud Sadeghi
2
,
Fereshteh Abasvandi
1
,
Mohammad Reza Shajari
1
,
Kamran Mohebi
1
,
Helen Ghandchi
1

  1. Breast Diseases Department, Breast Cancer Research Centre, Motamed Cancer Institute, ACECR, Tehran, Iran
  2. Medical Biology Research Centre, Kermanshah University of Medical Sciences, Kermanshah, Iran
Menopause Rev 2019; 18(2): 82-88
DOI: https://doi.org/10.5114/pm.2019.86833
Online publish date: 2019/06/28
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Aim of the study
The present study showed the clinicopathological characteristics and survival of early breast cancer (BC) patients.

Material and methods
A total of 236 patients were included in the study. The mean follow-up time was 59.5 months (range: 12-204 months). The inclusion criteria consisted of female patients aged > 20 years and early BC patients (stages I and IIA).

Results
The mean age at diagnosis was 51.2 years (range, 23-83 years), and 55.9% of patients were aged ≥ 50 years. Most patients (92.8%) did not have lymph node metastasis, and luminal B had the highest prevalence (54.2%) in patients. The eight-year overall survival (OS) and disease-free survival (DFS) rates were 98.3% and 92.3%, respectively. Stage IIA and Ki67 index ≥ 14% were more prevalent in the patients with tumour size of 2 ≤ T ≤ 5 cm compared to another tumour size group and Ki67 index.

Conclusions
The mean age at diagnosis in this study was in agreement with other studies reported in various areas, but with a higher percentage for elderly patients compared to some previous studies. In addition, the survival rate in the present study was higher than the results of previous studies. Future studies need to investigate these factors in a higher number of patients and in different areas and should select similar stages for early BC.

keywords:

early breast cancer, survival, recurrence, prognosis
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