Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis

Anna Olasińska-Wiśniewska; Tatiana Mularek-Kubzdela; Wojciech Seniuk; Piotr Bręborowicz; Hanna Wachowiak-Baszyńska; Jadwiga Kowal; Marek Grygier; Małgorzata Popiel; Włodzimierz Skorupski; Marcin Misterski; Aleksander Araszkiewicz; Romuald Ochotny; Stefan Grajek

eISSN: 1896-9151
ISSN: 1734-1922

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abstract:

Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis

Anna Olasińska-Wiśniewska

,

Tatiana Mularek-Kubzdela

,

Wojciech Seniuk

,

Piotr Bręborowicz

,

Hanna Wachowiak-Baszyńska

,

Jadwiga Kowal

,

Marek Grygier

,

Małgorzata Popiel

,

Włodzimierz Skorupski

,

Marcin Misterski

,

Aleksander Araszkiewicz

,

Romuald Ochotny

,

Stefan Grajek

Arch Med Sci 2009; 5, 1: 97-102

Online publish date: 2009/04/22

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AMA

Olasińska-Wiśniewska A, Mularek-Kubzdela T, Seniuk W, et al. Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis. Archives of Medical Science. 2009;5(1):97-102.

APA

Olasińska-Wiśniewska, A., Mularek-Kubzdela, T., Seniuk, W., Bręborowicz, P., Wachowiak-Baszyńska, H.,  & Kowal, J. et al. (2009). Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis. Archives of Medical Science, 5(1), 97-102.

Chicago

Olasińska-Wiśniewska, Anna, Tatiana Mularek-Kubzdela, Wojciech Seniuk, Piotr Bręborowicz, Hanna Wachowiak-Baszyńska, Jadwiga Kowal,  and Marek Grygier et al. 2009. "Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis". Archives of Medical Science 5 (1): 97-102.

Harvard

Olasińska-Wiśniewska, A., Mularek-Kubzdela, T., Seniuk, W., Bręborowicz, P., Wachowiak-Baszyńska, H., Kowal, J., Grygier, M., Popiel, M., Skorupski, W., Misterski, M., Araszkiewicz, A., Ochotny, R.,  and Grajek, S. (2009). Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis. Archives of Medical Science, 5(1), pp.97-102.

MLA

Olasińska-Wiśniewska, Anna et al. "Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis." Archives of Medical Science, vol. 5, no. 1, 2009, pp. 97-102.

Vancouver

Olasińska-Wiśniewska A, Mularek-Kubzdela T, Seniuk W, Bręborowicz P, Wachowiak-Baszyńska H, Kowal J et al. Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis. Archives of Medical Science. 2009;5(1):97-102.

Introduction: In previous decades, the analysis of heart rate variability (HRV) provided a non-invasive method of assessing autonomic influence for cardiovascular risk stratification. The aim of this study was to determine whether HRV analysis can still perform a similar function in the present day.
Material and methods: The study group consisted of 113 patients with acute myocardial infarction (AMI) treated with thrombolysis. In all patients echocardiography on the 10th day after myocardial infarction and 24-h Holter electrocardiographic recordings on the 12th day after myocardial infarction were performed. Five time domain measures were calculated from the time series of normal N-N intervals: SDNN, SDANN index, SDNN index, rMSSD and pNN50. The end points in follow-up were: death, non-fatal myocardial infarction (AMI) and unstable angina pectoris requiring hospitalization (API). The study group was divided into two subgroups on the basis of SDNN value and both groups were analysed.
Results: At follow-up (mean 65 months, range 36 to 96 months) we observed clinical events in 44 patients, including 17 deaths, 8 cases of AMI and 20 cases of API requiring hospitalization. In the multivariate analysis SDNN Ł 70 ms as well as left ventricle ejection fraction < 30% were independent predictors of death.
Conclusions: SDNN Ł 70 ms remains a significant predictor of death in patients with MI treated with thrombolysis.

keywords:

Prognostic value of decreased heart rate variability in long-term follow-up in patients with acute myocardial infarction treated with thrombolysis

Anna Olasińska-Wiśniewska , Tatiana Mularek-Kubzdela , Wojciech Seniuk , Piotr Bręborowicz , Hanna Wachowiak-Baszyńska , Jadwiga Kowal , Marek Grygier , Małgorzata Popiel , Włodzimierz Skorupski , Marcin Misterski , Aleksander Araszkiewicz , Romuald Ochotny , Stefan Grajek

heart rate variability, acute myocardial infarction