Psoriasis and cardiometabolic disorders

Julia Nowowiejska; Anna Baran; Iwona Flisiak

doi:10.5114/dr.2020.103887

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2020
vol. 107

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abstract:

Review paper

Psoriasis and cardiometabolic disorders

Julia Nowowiejska

¹

,

Anna Baran

¹

,

Iwona Flisiak

¹

Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland

Dermatol Rev/Przegl Dermatol 2020, 107, 508-520

DOI: https://doi.org/10.5114/dr.2020.103887

Online publish date: 2021/02/27

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Psoriasis is a chronic, inflammatory, autoimmune skin disease affecting 2–4% of general population. It is an important social issue, because of its confirmed associations with metabolic syndrome. Individals with psoriasis are at an increased risk of developing cardiovascular disorders and diabetes mellitus. Psoriasis and its comorbidities have multiple common pathogenic pathways including the chronic inflammatory process, immunological abnormalities, genetic links and different bioactive proteins secreted by the adipose tissue. Considering the above associations, it is advisable to perform screening tests in patients with psoriasis to detect metabolic disorders as they not only increase mortality in these individuals, but also decrease their life quality significantly. An essential issue is also the education and the improvement of doctor-patient relationship, as well as early introducing of preventive measures.

keywords:

Psoriasis and cardiometabolic disorders

Julia Nowowiejska 1 , Anna Baran 1 , Iwona Flisiak 1

psoriasis, metabolic syndrome, obesity, diabetes mellitus, dyslipidemia

Julia Nowowiejska

¹

,

Anna Baran

¹

,

Iwona Flisiak

¹