eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
Share:
Send email
Share:
abstract:
Original paper

Quality of life in adolescent and adult patients with persistent allergic rhinitis after one year of subcutaneous immunotherapy with a modified mite extract

Vanesa García-Paz
1
,
Laura Romero-Sánchez
2
,
Iván Carballeira-Anca
1
,
Carolina Gómez-Fariñas
3
,
Andrea Otero-Alonso
4
,
Soledad Sánchez-Sánchez
1
,
María González-Rivas
4
,
Leticia Vila-Sexto
5

  1. Allergy Department, Complexo Hospitalario Universitario de Ferrol, A Coruña, Spain
  2. Allergy Department, Complexo Hospitalario Universitario de Vigo, Pontevedra, Spain
  3. Allergy Department, Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain
  4. Allergy Department, Complexo Hospitalario Universitario de Santiago de Compostela, A Coruña, Spain
  5. Paediatric Allergy Unit, Department of Paediatrics, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain
Adv Dermatol Allergol
DOI: https://doi.org/10.5114/ada.2024.140520
Online publish date: 2024/06/12
View full text Get citation
 
Introduction:
Allergic rhinoconjunctivitis (AR) is an IgE-mediated inflammation of nasal and ocular mucosa after environmental allergen exposure, mainly by house dust mites (HDM). AR affects more than one third of the population worldwide and it is associated with loss of quality of life (QoL).

Aim:
To analyse the improvement in the QoL in 50 patients with moderate-persistent AR due to house HDM before and after receiving 1 year of subcutaneous specific aeroallergen immunotherapy treatment (SAIT).

Material and methods:
A prospective observational study was performed based on clinical practice in 50 patients with moderate-severe persistent AR due to HDM and candidates to SAIT. Forty-one patients completed the study. Patients were evaluated with the ESPRINT short-version QoL questionnaire, a score of medication use and visual analogue scale (VAS) symptom score, prior to and 12 months after SAIT.

Results:
Forty-one patients (25 women, mean age 26.9 years). Mean ESPRINT values prior to the start SAIT was 3.06 (moderate-severe) and 1 year after starting subcutaneous SAIT the mean value dropped in all patients to 0.88 (mild). The VAS score symptom dropped from 8.26 to 3.68. 97.56% of patients used 3 or more drugs (oral antihistamine, ophthalmic/intranasal antihistamine, intranasal corticosteroid and/or oral antileukotrienes) prior to starting SAIT, and 1 year after it, 58.53% used one on-demand medication to control symptoms, oral antihistamine or nasal spray, and not daily use.

Conclusions:
Subcutaneous SAIT seems to be a valid treatment in our patients with moderate-persistent AR due to HDM, since it reduces the ESPRINT score, VAS score and the use of medication. An improvement in the quality of life and satisfaction was observed by the patients themselves.

keywords:

quality of life, allergic rhinoconjunctivitis, rhinitis, ESPRINT, VAS, children, adolescent, adult, treatment, immunotherapy
FEATURED PRODUCTS
BOOKS
• Atopowe Zapalenie Skóry • Choroby alergiczne w praktyce lekarza rodzinnego • Alergologia – kompendium
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.